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* Copyright (c) 2007-2015 Broad Institute
*
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* of this software and associated documentation files (the "Software"), to deal
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*
* The above copyright notice and this permission notice shall be included in
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*
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package org.broad.igv.feature;
import org.broad.igv.AbstractHeadlessTest;
import org.junit.Test;
import java.util.List;
import static org.junit.Assert.*;
/**
* User: jacob
* Date: 2012-Oct-04
*/
public class CodonTest extends AbstractHeadlessTest {
private BasicFeature egfr;
@Override
public void setUp() throws Exception {
super.setUp();
egfr = (BasicFeature) FeatureDB.getFeature("egfr");
}
@Test
public void testGetCodon() {
// See http://www.ncbi.nlm.nih.gov/nuccore/NM_201283
//Note: This covers a break in exons
char[] expected = "MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLE".toCharArray();
tstGetCodon(egfr, expected);
}
@Test
public void testGetCodonNeg() {
//See http://www.ncbi.nlm.nih.gov/nuccore/NM_004985
String exp_string = "MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQV";
char[] expected = exp_string.toCharArray();
BasicFeature KRAS = (BasicFeature) FeatureDB.getFeature("KRAS");
tstGetCodon(KRAS, expected);
}
public void tstGetCodon(NamedFeature feature, char[] expected) {
BasicFeature bf = (BasicFeature) feature;
for (int pos = 0; pos < expected.length; pos++) {
Codon codon = bf.getCodon(genome, pos + 1);
assertEquals(expected[pos], codon.getAminoAcid().getSymbol());
}
}
//Check that there is no exception when loading an
@Test
public void testGetCodonInvalid() {
String geneName = "APOL1";
int proteinPos = 384;
//The position isn't valid for this transcript only
String invalidId = "NM_001136541";
//valid for these ids:
//NM_003661, NM_145343, NM_001136540
List<NamedFeature> featuresList = FeatureDB.getFeaturesList(geneName, 50, false);
for (NamedFeature feat : featuresList) {
BasicFeature bf = (BasicFeature) feat;
System.out.println(bf.getIdentifier());
Codon c = bf.getCodon(genome, proteinPos);
if (bf.getIdentifier().equals(invalidId)) {
assertNull(c);
} else {
assertNotNull(c);
assertTrue(c.isGenomePositionsSet());
}
}
}
}