/* * The MIT License (MIT) * * Copyright (c) 2007-2015 Broad Institute * * Permission is hereby granted, free of charge, to any person obtaining a copy * of this software and associated documentation files (the "Software"), to deal * in the Software without restriction, including without limitation the rights * to use, copy, modify, merge, publish, distribute, sublicense, and/or sell * copies of the Software, and to permit persons to whom the Software is * furnished to do so, subject to the following conditions: * * The above copyright notice and this permission notice shall be included in * all copies or substantial portions of the Software. * * * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE * AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, * OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN * THE SOFTWARE. */ package org.broad.igv.variant.util; import org.broad.igv.feature.genome.Genome; import org.broad.igv.feature.tribble.CodecFactory; import htsjdk.tribble.AbstractFeatureReader; import htsjdk.tribble.FeatureCodec; import htsjdk.variant.variantcontext.VariantContext; import htsjdk.variant.vcf.VCFCodec; import java.io.BufferedWriter; import java.io.FileWriter; import java.io.IOException; import java.io.PrintWriter; import java.util.Iterator; /** * Utility class to convert a VCF to a BED file. Genotypes if any are lost in this converstion * * @author jrobinso * @date Jan 22, 2011 */ public class VCFtoBed { public static void main(String[] args) throws IOException { convert(args[0], args[1]); } public static void convert(String vcfFile, String bedFile) throws IOException { AbstractFeatureReader basicReader = null; PrintWriter writer = null; try { writer = new PrintWriter(new BufferedWriter(new FileWriter(bedFile))); Genome genome = null; // Don't do alias converting FeatureCodec codec = CodecFactory.getCodec(vcfFile, genome); boolean isVCF = codec.getClass().isAssignableFrom(VCFCodec.class); basicReader = AbstractFeatureReader.getFeatureReader(vcfFile, codec, true); Iterator<VariantContext> iter = basicReader.iterator(); while (iter.hasNext()) { VariantContext vc = iter.next(); String chr = vc.getChr(); if (!chr.startsWith("chr")) { chr = "chr" + chr; } int start = vc.getStart() - 1; int end = vc.getEnd(); String id = vc.getID(); if(id == null) { id = "."; } String af = vc.getAttributeAsString("AF", ""); writer.println(chr + "\t" + start + "\t" + end + "\t" + id + "\t" + af); } } finally { if (basicReader != null) basicReader.close(); if (writer != null) writer.close(); } } }