/* * #%L * gitools-core * %% * Copyright (C) 2013 Universitat Pompeu Fabra - Biomedical Genomics group * %% * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as * published by the Free Software Foundation, either version 3 of the * License, or (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public * License along with this program. If not, see * <http://www.gnu.org/licenses/gpl-3.0.html>. * #L% */ package org.gitools.analysis.stats.mtc; import org.apache.commons.math3.util.FastMath; import org.gitools.api.matrix.AbstractMatrixFunction; import org.gitools.api.matrix.IMatrixIterable; import org.gitools.api.matrix.IMatrixPosition; import org.gitools.matrix.filter.NotNullPredicate; import java.util.Arrays; import java.util.HashMap; import java.util.Map; public class BenjaminiHochbergFdrMtcFunction extends AbstractMatrixFunction<Double, Double> { private int n = 0; private Map<String, Integer> ranks; public BenjaminiHochbergFdrMtcFunction() { } @Override public void onBeforeIterate(IMatrixIterable<Double> parentIterable) { ranks = new HashMap<>((int) parentIterable.size()); n = 0; int rank = 0; Double lastValue = -1.0; IMatrixIterable<Double> sortedIterable = parentIterable.filter(new NotNullPredicate<Double>()).sort(); for (Double value : sortedIterable) { n++; if (!lastValue.equals(value)) { rank++; } String hash = hashKey(sortedIterable.getPosition()); ranks.put(hash, rank); lastValue = value; } } @Override public Double apply(Double value, IMatrixPosition position) { if (value == null) { return null; } int rank = ranks.get(hashKey(position)); double result = FastMath.min(1.0, value * n / rank); return result; } private String hashKey(IMatrixPosition position) { //TODO improve performance return Arrays.toString(position.toVector()); } }