/* * PartitionedTreeModelParser.java * * Copyright (c) 2002-2015 Alexei Drummond, Andrew Rambaut and Marc Suchard * * This file is part of BEAST. * See the NOTICE file distributed with this work for additional * information regarding copyright ownership and licensing. * * BEAST is free software; you can redistribute it and/or modify * it under the terms of the GNU Lesser General Public License as * published by the Free Software Foundation; either version 2 * of the License, or (at your option) any later version. * * BEAST is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU Lesser General Public License for more details. * * You should have received a copy of the GNU Lesser General Public * License along with BEAST; if not, write to the * Free Software Foundation, Inc., 51 Franklin St, Fifth Floor, * Boston, MA 02110-1301 USA */ package dr.evomodel.epidemiology.casetocase; import dr.evolution.tree.NodeRef; import dr.evolution.tree.Tree; import dr.evolution.tree.TreeUtils; import dr.evolution.util.Date; import dr.evolution.util.Taxon; import dr.evolution.util.TaxonList; import dr.inference.model.CompoundParameter; import dr.inference.model.Parameter; import dr.inference.model.ParameterParser; import dr.xml.*; import java.util.logging.Logger; /** * For now, this is basically a copy of TreeModelParser. Later, initialisation options for the partitioning should be * moved here * * @author Alexei Drummond * @author Matthew Hall */ public class PartitionedTreeModelParser extends AbstractXMLObjectParser { public static final String ROOT_HEIGHT = "rootHeight"; public static final String LEAF_HEIGHT = "leafHeight"; public static final String LEAF_TRAIT = "leafTrait"; public static final String NODE_HEIGHTS = "nodeHeights"; public static final String NODE_RATES = "nodeRates"; public static final String NODE_TRAITS = "nodeTraits"; public static final String MULTIVARIATE_TRAIT = "traitDimension"; public static final String INITIAL_VALUE = "initialValue"; public static final String ROOT_NODE = "rootNode"; public static final String INTERNAL_NODES = "internalNodes"; public static final String LEAF_NODES = "leafNodes"; public static final String LEAF_HEIGHTS = "leafHeights"; public static final String FIRE_TREE_EVENTS = "fireTreeEvents"; public static final String TAXON = "taxon"; public static final String NAME = "name"; public static final String OUTBREAK = "outbreak"; public static final String STARTING_TT_FILE = "startingTransmissionTreeFile"; public PartitionedTreeModelParser() { rules = new XMLSyntaxRule[]{ new ElementRule(Tree.class), new ElementRule(ROOT_HEIGHT, Parameter.class, "A parameter definition with id only (cannot be a reference!)", false), new ElementRule(NODE_HEIGHTS, new XMLSyntaxRule[]{ AttributeRule.newBooleanRule(ROOT_NODE, true, "If true the root height is included in the parameter"), AttributeRule.newBooleanRule(INTERNAL_NODES, true, "If true the internal node heights (minus the root) are included in the parameter"), new ElementRule(Parameter.class, "A parameter definition with id only (cannot be a reference!)") }, 1, Integer.MAX_VALUE), new ElementRule(LEAF_HEIGHT, new XMLSyntaxRule[]{ AttributeRule.newStringRule(TAXON, false, "The name of the taxon for the leaf"), new ElementRule(Parameter.class, "A parameter definition with id only (cannot be a reference!)") }, 0, Integer.MAX_VALUE), new ElementRule(NODE_TRAITS, new XMLSyntaxRule[]{ AttributeRule.newStringRule(NAME, false, "The name of the trait attribute in the taxa"), AttributeRule.newBooleanRule(ROOT_NODE, true, "If true the root trait is included in the parameter"), AttributeRule.newBooleanRule(INTERNAL_NODES, true, "If true the internal node traits (minus the root) are included in the parameter"), AttributeRule.newBooleanRule(LEAF_NODES, true, "If true the leaf node traits are included in the parameter"), AttributeRule.newIntegerRule(MULTIVARIATE_TRAIT, true, "The number of dimensions (if multivariate)"), AttributeRule.newDoubleRule(INITIAL_VALUE, true, "The initial value(s)"), AttributeRule.newBooleanRule(FIRE_TREE_EVENTS, true, "Whether to fire tree events if the traits change"), new ElementRule(Parameter.class, "A parameter definition with id only (cannot be a reference!)") }, 0, Integer.MAX_VALUE), new ElementRule(NODE_RATES, new XMLSyntaxRule[]{ AttributeRule.newBooleanRule(ROOT_NODE, true, "If true the root rate is included in the parameter"), AttributeRule.newBooleanRule(INTERNAL_NODES, true, "If true the internal node rate (minus the root) are included in the parameter"), AttributeRule.newBooleanRule(LEAF_NODES, true, "If true the leaf node rate are included in the parameter"), AttributeRule.newDoubleRule(INITIAL_VALUE, true, "The initial value(s)"), new ElementRule(Parameter.class, "A parameter definition with id only (cannot be a reference!)") }, 0, Integer.MAX_VALUE), new ElementRule(LEAF_TRAIT, new XMLSyntaxRule[]{ AttributeRule.newStringRule(TAXON, false, "The name of the taxon for the leaf"), AttributeRule.newStringRule(NAME, false, "The name of the trait attribute in the taxa"), new ElementRule(Parameter.class, "A parameter definition with id only (cannot be a reference!)") }, 0, Integer.MAX_VALUE), new ElementRule(LEAF_HEIGHTS, new XMLSyntaxRule[]{ new ElementRule(TaxonList.class, "A set of taxa for which leaf heights are required"), new ElementRule(Parameter.class, "A compound parameter containing the leaf heights") }, true), new ElementRule(OUTBREAK, AbstractOutbreak.class, "The case data"), AttributeRule.newStringRule(STARTING_TT_FILE, true) }; } public String getParserName() { return PartitionedTreeModel.PARTITIONED_TREE_MODEL; } /** * @return a tree object based on the XML element it was passed. */ public Object parseXMLObject(XMLObject xo) throws XMLParseException { Tree tree = (Tree) xo.getChild(Tree.class); AbstractOutbreak outbreak = (AbstractOutbreak)xo.getElementFirstChild(OUTBREAK); PartitionedTreeModel treeModel; if(xo.hasAttribute(STARTING_TT_FILE)){ treeModel = new PartitionedTreeModel(xo.getId(), tree, outbreak, xo.getStringAttribute(STARTING_TT_FILE)); } else { treeModel = new PartitionedTreeModel(xo.getId(), tree, outbreak); } Logger.getLogger("dr.evomodel").info("Creating the partitioned tree model, '" + xo.getId() + "'"); for (int i = 0; i < xo.getChildCount(); i++) { if (xo.getChild(i) instanceof XMLObject) { XMLObject cxo = (XMLObject) xo.getChild(i); if (cxo.getName().equals(ROOT_HEIGHT)) { ParameterParser.replaceParameter(cxo, treeModel.getRootHeightParameter()); } else if (cxo.getName().equals(LEAF_HEIGHT)) { String taxonName; if (cxo.hasAttribute(TAXON)) { taxonName = cxo.getStringAttribute(TAXON); } else { throw new XMLParseException("taxa element missing from leafHeight element in treeModel element"); } int index = treeModel.getTaxonIndex(taxonName); if (index == -1) { throw new XMLParseException("taxon " + taxonName + " not found for leafHeight element in treeModel element"); } NodeRef node = treeModel.getExternalNode(index); Parameter newParameter = treeModel.getLeafHeightParameter(node); ParameterParser.replaceParameter(cxo, newParameter); Taxon taxon = treeModel.getTaxon(index); setPrecisionBounds(newParameter, taxon); } else if (cxo.getName().equals(LEAF_HEIGHTS)) { // get a set of leaf height parameters out as a compound parameter... TaxonList taxa = (TaxonList)cxo.getChild(TaxonList.class); Parameter offsetParameter = (Parameter)cxo.getChild(Parameter.class); CompoundParameter leafHeights = new CompoundParameter("leafHeights"); for (Taxon taxon : taxa) { int index = treeModel.getTaxonIndex(taxon); if (index == -1) { throw new XMLParseException("taxon " + taxon.getId() + " not found for leafHeight element in treeModel element"); } NodeRef node = treeModel.getExternalNode(index); Parameter newParameter = treeModel.getLeafHeightParameter(node); leafHeights.addParameter(newParameter); setPrecisionBounds(newParameter, taxon); } ParameterParser.replaceParameter(cxo, leafHeights); } else if (cxo.getName().equals(NODE_HEIGHTS)) { boolean rootNode = cxo.getAttribute(ROOT_NODE, false); boolean internalNodes = cxo.getAttribute(INTERNAL_NODES, false); boolean leafNodes = cxo.getAttribute(LEAF_NODES, false); if (!rootNode && !internalNodes && !leafNodes) { throw new XMLParseException("one or more of root, internal or leaf nodes must be selected for the nodeHeights element"); } ParameterParser.replaceParameter(cxo, treeModel.createNodeHeightsParameter(rootNode, internalNodes, leafNodes)); } else if (cxo.getName().equals(NODE_RATES)) { boolean rootNode = cxo.getAttribute(ROOT_NODE, false); boolean internalNodes = cxo.getAttribute(INTERNAL_NODES, false); boolean leafNodes = cxo.getAttribute(LEAF_NODES, false); double[] initialValues = null; if (cxo.hasAttribute(INITIAL_VALUE)) { initialValues = cxo.getDoubleArrayAttribute(INITIAL_VALUE); } if (!rootNode && !internalNodes && !leafNodes) { throw new XMLParseException("one or more of root, internal or leaf nodes must be selected for the nodeRates element"); } ParameterParser.replaceParameter(cxo, treeModel.createNodeRatesParameter(initialValues, rootNode, internalNodes, leafNodes)); } else if (cxo.getName().equals(NODE_TRAITS)) { boolean rootNode = cxo.getAttribute(ROOT_NODE, false); boolean internalNodes = cxo.getAttribute(INTERNAL_NODES, false); boolean leafNodes = cxo.getAttribute(LEAF_NODES, false); boolean fireTreeEvents = cxo.getAttribute(FIRE_TREE_EVENTS, false); String name = cxo.getAttribute(NAME, "trait"); int dim = cxo.getAttribute(MULTIVARIATE_TRAIT, 1); double[] initialValues = null; if (cxo.hasAttribute(INITIAL_VALUE)) { initialValues = cxo.getDoubleArrayAttribute(INITIAL_VALUE); } if (!rootNode && !internalNodes && !leafNodes) { throw new XMLParseException("one or more of root, internal or leaf nodes must be selected for the nodeTraits element"); } ParameterParser.replaceParameter(cxo, treeModel.createNodeTraitsParameter(name, dim, initialValues, rootNode, internalNodes, leafNodes, fireTreeEvents)); } else if (cxo.getName().equals(LEAF_TRAIT)) { String name = cxo.getAttribute(NAME, "trait"); String taxonName; if (cxo.hasAttribute(TAXON)) { taxonName = cxo.getStringAttribute(TAXON); } else { throw new XMLParseException("taxa element missing from leafTrait element in treeModel element"); } int index = treeModel.getTaxonIndex(taxonName); if (index == -1) { throw new XMLParseException("taxon '" + taxonName + "' not found for leafTrait element in treeModel element"); } NodeRef node = treeModel.getExternalNode(index); Parameter parameter = treeModel.getNodeTraitParameter(node, name); if (parameter == null) throw new XMLParseException("trait '" + name + "' not found for leafTrait (taxon, " + taxonName + ") element in treeModel element"); ParameterParser.replaceParameter(cxo, parameter); } else { if(!cxo.getName().equals(OUTBREAK)) { throw new XMLParseException("illegal child element in " + getParserName() + ": " + cxo.getName()); } } } else if (xo.getChild(i) instanceof Tree) { // do nothing - already handled } else { throw new XMLParseException("illegal child element in " + getParserName() + ": " + xo.getChildName(i) + " " + xo.getChild(i)); } } // AR this is doubling up the number of bounds on each node. // treeModel.setupHeightBounds(); //System.err.println("done constructing treeModel"); Logger.getLogger("dr.evomodel").info(" initial tree topology = " + TreeUtils.uniqueNewick(treeModel, treeModel.getRoot())); Logger.getLogger("dr.evomodel").info(" tree height = " + treeModel.getNodeHeight(treeModel.getRoot())); return treeModel; } private void setPrecisionBounds(Parameter newParameter, Taxon taxon) { Date date = taxon.getDate(); if (date != null) { double precision = date.getPrecision(); if (precision > 0.0) { // taxon date not specified to exact value so add appropriate bounds double upper = Taxon.getHeightFromDate(date); double lower = Taxon.getHeightFromDate(date); if (date.isBackwards()) { upper += precision; } else { lower -= precision; } // set the bounds for the given precision newParameter.addBounds(new Parameter.DefaultBounds(upper, lower, 1)); // set the initial value to be mid-point newParameter.setParameterValue(0, (upper + lower) / 2); } } } //************************************************************************ // AbstractXMLObjectParser implementation //************************************************************************ public String getParserDescription() { return "This element represents a model of a phylogenetic tree together with the partitioning of its nodes " + "into connected subgraphs to represent the transmission tree."; } public Class getReturnType() { return PartitionedTreeModel.class; } public XMLSyntaxRule[] getSyntaxRules() { return rules; } private final XMLSyntaxRule[] rules; }