/* * The MIT License * * Copyright (c) 2016 The Broad Institute * * Permission is hereby granted, free of charge, to any person obtaining a copy * of this software and associated documentation files (the "Software"), to deal * in the Software without restriction, including without limitation the rights * to use, copy, modify, merge, publish, distribute, sublicense, and/or sell * copies of the Software, and to permit persons to whom the Software is * furnished to do so, subject to the following conditions: * * The above copyright notice and this permission notice shall be included in * all copies or substantial portions of the Software. * * THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR * IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY, * FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE * AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER * LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM, * OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN * THE SOFTWARE. */ package picard.analysis; import java.util.ArrayList; import java.util.Arrays; /** * Class for managing a list of Counters of integer, * provides methods to access data from Counters with respect to an offset. * Each Counter represents a certain region of a processed sequence starting from offset and * can accumulate some value for each locus of this sequence, for instance, read coverage. * @author Mariia_Zueva@epam.com, EPAM Systems, Inc. <www.epam.com> */ public class CounterManager { /** * Length of inner Counter arrays */ private final int arrayLength; /** * Proposed length of processed reads */ private final int readLength; /** * Current offset from the start of the processed sequence. If offset = 100, this means, that value in * Counter arrays at index 0, represents the 100th position of the sequence. */ private int offset = 0; /** * List of Counter arrays for managing */ private final ArrayList<Counter> arrays = new ArrayList<>(2); /** * Constructor creates new CounterManager without any Counters, * counters are added to CounterManager via newCounter() method * * @param arrayLength length of inner Counter arrays * @param readLength proposed length of processed reads */ public CounterManager(final int arrayLength, int readLength) { this.arrayLength = arrayLength; this.readLength = readLength; } /** * Method added for use in unit tests * * @return offset from the reference sequence, that is represented by index 0 of {@link picard.analysis.CounterManager.Counter} arrays. */ int getOffset() { return offset; } /** * Method added for use in unit tests * * @param offset from the reference sequence, that will be represented by index 0 of {@link picard.analysis.CounterManager.Counter} arrays. */ void setOffset(int offset) { this.offset = offset; } /** * Method checks that new locus position is not out of bounds of Counter arrays and there is enough * space in them to hold information on at least one more read of length {@link this#readLength}. * If there is no free space, but there is accumulated information in Counter arrays after new locus position * that we may need, the arrays are rebased, so that 0 index of arrays represents new locus position. * In other case, we just clear the arrays. * * @param locusPosition position in the reference sequence, * that will be represented by index 0 of {@link picard.analysis.CounterManager.Counter} arrays. */ public void checkOutOfBounds(int locusPosition) { if (locusPosition - offset + readLength >= arrayLength) { if (locusPosition - offset < arrayLength) { rebase(locusPosition); } else { clear(); offset = locusPosition; } } } /** * Rebases inner Counter arrays so that 0 index of array represents the new locus position * * @param locusPosition position in the reference sequence, * that will be represented by index 0 of {@link picard.analysis.CounterManager.Counter} arrays. */ private void rebase(int locusPosition) { if (locusPosition < offset) { throw new IllegalArgumentException("Position in the reference sequence is lesser than offset."); } for (Counter counter : arrays) { final int[] array = counter.array; final int skipLength = locusPosition - offset; System.arraycopy(array, skipLength, array, 0, arrayLength - skipLength); Arrays.fill(array, arrayLength - skipLength, arrayLength, 0); } offset = locusPosition; } /** * Clears all inner Counter arrays */ public void clear() { for (Counter counter : arrays) { final int[] array = counter.array; Arrays.fill(array, 0); } offset = 0; } /** * Creates a new Counter object and adds it to the list of managed Counters. * * @return {@link picard.analysis.CounterManager.Counter}, that will be managed by current {@link picard.analysis.CounterManager} */ public Counter newCounter() { final Counter counter = new Counter(arrayLength); arrays.add(counter); return counter; } /** * Class represents an integer array with methods to increment and get the values from it with respect * to offset of outer {@link picard.analysis.CounterManager}. */ public class Counter { /** * Inner array to store accumulated values */ private final int[] array; /** * @param arrayLength length of the inner array */ private Counter(int arrayLength) { array = new int[arrayLength]; } /** * Increments value corresponding to reference sequence index * * @param index in the reference sequence */ public void increment(int index) { checkIndex(index); array[index - offset]++; } /** * @param index in the reference sequence * @return value from the inner array, corresponding to input reference index */ public int get(int index) { checkIndex(index); return array[index - offset]; } private void checkIndex(int index) { if ((index - offset) < 0 || (index - offset) >= array.length) { throw new ArrayIndexOutOfBoundsException("The requested index " + index + " is out of counter bounds. " + "Possible cause of exception can be wrong READ_LENGTH parameter (much smaller than actual read length)"); } } } }