/******************************************************************************* * GenPlay, Einstein Genome Analyzer * Copyright (C) 2009, 2014 Albert Einstein College of Medicine * * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as published by * the Free Software Foundation, either version 3 of the License, or * (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program. If not, see <http://www.gnu.org/licenses/>. * Authors: Julien Lajugie <julien.lajugie@einstein.yu.edu> * Nicolas Fourel <nicolas.fourel@einstein.yu.edu> * Eric Bouhassira <eric.bouhassira@einstein.yu.edu> * * Website: <http://genplay.einstein.yu.edu> ******************************************************************************/ package edu.yu.einstein.genplay.dataStructure.list.genomeWideList.geneList; import java.io.IOException; import java.util.ArrayList; import java.util.Collection; import java.util.List; import java.util.concurrent.Callable; import java.util.concurrent.ExecutionException; import edu.yu.einstein.genplay.core.IO.dataReader.GeneReader; import edu.yu.einstein.genplay.core.manager.project.ProjectChromosomes; import edu.yu.einstein.genplay.core.manager.project.ProjectManager; import edu.yu.einstein.genplay.core.operationPool.OperationPool; import edu.yu.einstein.genplay.dataStructure.chromosome.Chromosome; import edu.yu.einstein.genplay.dataStructure.enums.GeneScoreType; import edu.yu.einstein.genplay.dataStructure.enums.Strand; import edu.yu.einstein.genplay.dataStructure.gene.Gene; import edu.yu.einstein.genplay.dataStructure.gene.SimpleGene; import edu.yu.einstein.genplay.dataStructure.list.chromosomeWideList.SCWListView.SCWListViewBuilder; import edu.yu.einstein.genplay.dataStructure.list.chromosomeWideList.SCWListView.generic.GenericSCWListViewBuilder; import edu.yu.einstein.genplay.dataStructure.list.chromosomeWideList.geneListView.GeneListViewBuilder; import edu.yu.einstein.genplay.dataStructure.list.genomeWideList.ListOfListViewBuilder; import edu.yu.einstein.genplay.dataStructure.list.genomeWideList.SCWList.SCWList; import edu.yu.einstein.genplay.dataStructure.list.listView.ListView; import edu.yu.einstein.genplay.dataStructure.list.listView.ListViewBuilder; import edu.yu.einstein.genplay.dataStructure.scoredChromosomeWindow.ScoredChromosomeWindow; import edu.yu.einstein.genplay.exception.exceptions.InvalidChromosomeException; import edu.yu.einstein.genplay.exception.exceptions.ObjectAlreadyBuiltException; /** * Factory class for vending standard {@link GeneList} objects * @author Julien Lajugie */ public class GeneListFactory { /** * Creates a {@link GeneList} from the data retrieved by the specified {@link GeneReader}. * @param geneReader a {@link GeneReader} * @return a {@link GeneList} * @throws ExecutionException * @throws InterruptedException * @throws CloneNotSupportedException * @throws IOException * @throws ObjectAlreadyBuiltException * @throws InvalidChromosomeException */ public static GeneList createGeneList(GeneReader geneReader) throws InterruptedException, ExecutionException, CloneNotSupportedException, InvalidChromosomeException, ObjectAlreadyBuiltException, IOException { GeneListViewBuilder lvBuilderPrototype = new GeneListViewBuilder(); ListOfListViewBuilder<Gene> builder = new ListOfListViewBuilder<Gene>(lvBuilderPrototype); while (geneReader.readItem()) { Gene currentGene = new SimpleGene( geneReader.getName(), geneReader.getStrand(), geneReader.getStart(), geneReader.getStop(), geneReader.getScore(), geneReader.getUTR5Bound(), geneReader.getUTR3Bound(), geneReader.getExons()); builder.addElementToBuild(geneReader.getChromosome(), currentGene); } String geneDBURL = geneReader.getGeneDBURL(); GeneScoreType geneScoreType = geneReader.getGeneScoreType(); return new SimpleGeneList(builder.getGenomicList(), geneScoreType, geneDBURL); } /** * Creates a {@link GeneList} from a {@link SCWList}. * It creates one gene per window with a single exon having the same start, stop and score as the window. * @param scoredChromosomeWindowList * @return a {@link GeneList} * @throws InterruptedException * @throws ExecutionException */ public static GeneList createGeneList(SCWList scoredChromosomeWindowList) throws InterruptedException, ExecutionException { ProjectChromosomes projectChromosomes = ProjectManager.getInstance().getProjectChromosomes(); final OperationPool op = OperationPool.getInstance(); final Collection<Callable<ListView<Gene>>> threadList = new ArrayList<Callable<ListView<Gene>>>(); for (int i = 0; i < scoredChromosomeWindowList.size(); i++) { final ListView<ScoredChromosomeWindow> currentList = scoredChromosomeWindowList.get(i); final Chromosome chromosome = projectChromosomes.get(i); final String prefixName = chromosome.getName() + "."; Callable<ListView<Gene>> currentThread = new Callable<ListView<Gene>>() { @Override public ListView<Gene> call() throws Exception { ListViewBuilder<Gene> geneListBuilder = new GeneListViewBuilder(); for (int j = 0; j < currentList.size(); j++) { ScoredChromosomeWindow currentWindow = currentList.get(j); String name = prefixName + (j + 1); int start = currentWindow.getStart(); int stop = currentWindow.getStop(); float score = currentWindow.getScore(); Strand strand = Strand.FIVE; SCWListViewBuilder exonListBuilder = new GenericSCWListViewBuilder(); exonListBuilder.addElementToBuild(currentWindow.getStart(), currentWindow.getStop(), currentWindow.getScore()); Gene geneToAdd = new SimpleGene(name, strand, start, stop, score, exonListBuilder.getListView()); geneListBuilder.addElementToBuild(geneToAdd); } // tell the operation pool that a chromosome is done op.notifyDone(); return geneListBuilder.getListView(); } }; threadList.add(currentThread); } List<ListView<Gene>> result = op.startPool(threadList); return new SimpleGeneList(result, null, null); } }