/******************************************************************************* * GenPlay, Einstein Genome Analyzer * Copyright (C) 2009, 2014 Albert Einstein College of Medicine * * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as published by * the Free Software Foundation, either version 3 of the License, or * (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program. If not, see <http://www.gnu.org/licenses/>. * Authors: Julien Lajugie <julien.lajugie@einstein.yu.edu> * Nicolas Fourel <nicolas.fourel@einstein.yu.edu> * Eric Bouhassira <eric.bouhassira@einstein.yu.edu> * * Website: <http://genplay.einstein.yu.edu> ******************************************************************************/ package edu.yu.einstein.genplay.core.operation.geneList; import java.util.ArrayList; import java.util.List; import java.util.concurrent.Callable; import edu.yu.einstein.genplay.core.operation.Operation; import edu.yu.einstein.genplay.core.operationPool.OperationPool; import edu.yu.einstein.genplay.dataStructure.gene.Gene; import edu.yu.einstein.genplay.dataStructure.list.chromosomeWideList.geneListView.GeneListViewBuilder; import edu.yu.einstein.genplay.dataStructure.list.genomeWideList.geneList.GeneList; import edu.yu.einstein.genplay.dataStructure.list.genomeWideList.geneList.SimpleGeneList; import edu.yu.einstein.genplay.dataStructure.list.listView.ListView; import edu.yu.einstein.genplay.dataStructure.list.listView.ListViewBuilder; /** * Removes the genes with an overall RPKM between two specified thresholds * @author Julien Lajugie */ public class GLOFilterBandStop implements Operation<GeneList> { private final GeneList geneList; // input GeneList private final float lowThreshold; // low bound private final float highThreshold; // high bound private boolean stopped = false; // true if the operation must be stopped /** * Creates an instance of {@link GLOFilterBandStop} * @param geneList input {@link GeneList} * @param lowThreshold low threshold * @param highThreshold high threshold */ public GLOFilterBandStop(GeneList geneList, float lowThreshold, float highThreshold) { this.geneList = geneList; this.lowThreshold = lowThreshold; this.highThreshold = highThreshold; } @Override public GeneList compute() throws Exception { if (lowThreshold >= highThreshold) { throw new IllegalArgumentException("The high threshold must be greater than the low one"); } final OperationPool op = OperationPool.getInstance(); final List<Callable<ListView<Gene>>> threadList = new ArrayList<Callable<ListView<Gene>>>(); for (final ListView<Gene> currentList: geneList) { Callable<ListView<Gene>> currentThread = new Callable<ListView<Gene>>() { @Override public ListView<Gene> call() throws Exception { ListViewBuilder<Gene> resultLVBuilder = new GeneListViewBuilder(); if ((currentList != null) && (currentList.size() != 0)) { for (int j = 0; (j < currentList.size()) && !stopped; j++) { Float currentValue = currentList.get(j).getScore(); if ((currentValue == null) || ((currentValue < lowThreshold) && (currentValue > highThreshold))) { Gene geneToAdd = currentList.get(j); resultLVBuilder.addElementToBuild(geneToAdd); } } } // tell the operation pool that a chromosome is done op.notifyDone(); return resultLVBuilder.getListView(); } }; threadList.add(currentThread); } List<ListView<Gene>> result = op.startPool(threadList); if (result != null) { GeneList resultList = new SimpleGeneList(result, geneList.getGeneScoreType(), geneList.getGeneDBURL()); return resultList; } else { return null; } } @Override public String getDescription() { return "Operation: Band-Stop Filter, Low Threshold = " + lowThreshold + ", High Threshold = " + highThreshold; } @Override public String getProcessingDescription() { return "Filtering"; } @Override public int getStepCount() { return 1; } @Override public void stop() { stopped = true; } }