/* VARNA is a tool for the automated drawing, visualization and annotation of the secondary structure of RNA, designed as a companion software for web servers and databases. Copyright (C) 2008 Kevin Darty, Alain Denise and Yann Ponty. electronic mail : Yann.Ponty@lri.fr paper mail : LRI, bat 490 Universit� Paris-Sud 91405 Orsay Cedex France This file is part of VARNA version 3.1. VARNA version 3.1 is free software: you can redistribute it and/or modify it under the terms of the GNU General Public License as published by the Free Software Foundation, either version 3 of the License, or (at your option) any later version. VARNA version 3.1 is distributed in the hope that it will be useful, but WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License for more details. You should have received a copy of the GNU General Public License along with VARNA version 3.1. 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END OF TERMS AND CONDITIONS */ package fr.orsay.lri.varna; import java.awt.BasicStroke; import java.awt.Color; import java.awt.Component; import java.awt.Dimension; import java.awt.Font; import java.awt.Graphics; import java.awt.Graphics2D; import java.awt.Point; import java.awt.Rectangle; import java.awt.RenderingHints; import java.awt.Shape; import java.awt.geom.AffineTransform; import java.awt.geom.GeneralPath; import java.awt.geom.Point2D; import java.awt.geom.Rectangle2D; import java.awt.print.PrinterException; import java.awt.print.PrinterJob; import java.io.FileInputStream; import java.io.FileNotFoundException; import java.io.FileOutputStream; import java.io.IOException; import java.io.InputStream; import java.io.ObjectInputStream; import java.io.ObjectOutputStream; import java.io.Reader; import java.text.NumberFormat; import java.util.ArrayList; import java.util.Collection; import java.util.Hashtable; import java.util.Set; import javax.print.attribute.HashPrintRequestAttributeSet; import javax.print.attribute.PrintRequestAttributeSet; import javax.swing.JOptionPane; import javax.swing.JPanel; import javax.swing.undo.UndoManager; import fr.orsay.lri.varna.controlers.ControleurBlinkingThread; import fr.orsay.lri.varna.controlers.ControleurClicMovement; import fr.orsay.lri.varna.controlers.ControleurDraggedMolette; import fr.orsay.lri.varna.controlers.ControleurInterpolator; import fr.orsay.lri.varna.controlers.ControleurMolette; import fr.orsay.lri.varna.controlers.ControleurVARNAPanelKeys; import fr.orsay.lri.varna.exceptions.ExceptionFileFormatOrSyntax; import fr.orsay.lri.varna.exceptions.ExceptionLoadingFailed; import fr.orsay.lri.varna.exceptions.ExceptionNAViewAlgorithm; import fr.orsay.lri.varna.exceptions.ExceptionNonEqualLength; import fr.orsay.lri.varna.exceptions.ExceptionUnmatchedClosingParentheses; import fr.orsay.lri.varna.factories.RNAFactory; import fr.orsay.lri.varna.interfaces.InterfaceVARNAListener; import fr.orsay.lri.varna.interfaces.InterfaceVARNARNAListener; import fr.orsay.lri.varna.interfaces.InterfaceVARNASelectionListener; import fr.orsay.lri.varna.models.BaseList; import fr.orsay.lri.varna.models.FullBackup; import fr.orsay.lri.varna.models.VARNAConfig; import fr.orsay.lri.varna.models.annotations.ChemProbAnnotation; import fr.orsay.lri.varna.models.annotations.HighlightRegionAnnotation; import fr.orsay.lri.varna.models.annotations.TextAnnotation; import fr.orsay.lri.varna.models.export.SwingGraphics; import fr.orsay.lri.varna.models.export.VueVARNAGraphics; import fr.orsay.lri.varna.models.rna.Mapping; import fr.orsay.lri.varna.models.rna.ModeleBase; import fr.orsay.lri.varna.models.rna.ModeleBaseNucleotide; import fr.orsay.lri.varna.models.rna.ModeleBasesComparison; import fr.orsay.lri.varna.models.rna.ModeleColorMap; import fr.orsay.lri.varna.models.rna.ModeleBP; import fr.orsay.lri.varna.models.rna.RNA; import fr.orsay.lri.varna.views.VueMenu; import fr.orsay.lri.varna.views.VueUI; /** * The RNA 2D Panel is a lightweight component that allows for an automatic * basic drawing of an RNA secondary structures. The drawing algorithms do not * ensure a non-overlapping drawing of helices, thus it is possible to "spin the * helices" through a click-and-drag approach. A typical usage of the class from * within the constructor of a <code>JFrame</code> would be the following:<br/> * <code> *   VARNAPanel _rna = new VARNAPanel("CCCCAUAUGGGGACC","((((....))))...");<br /> *   this.getContentPane().add(_rna); * </code> * * @version 3.4 * @author Yann Ponty & Kevin Darty * */ public class VARNAPanel extends JPanel { /** * */ private static final long serialVersionUID = 8194421570308956001L; private RNA _RNA = new RNA(); private boolean _debug = false; private VARNAConfig _conf = new VARNAConfig(); private ArrayList<InterfaceVARNAListener> _VARNAListeners = new ArrayList<InterfaceVARNAListener>(); private ArrayList<InterfaceVARNASelectionListener> _selectionListeners = new ArrayList<InterfaceVARNASelectionListener>(); private ArrayList<InterfaceVARNARNAListener> _RNAListeners = new ArrayList<InterfaceVARNARNAListener>(); UndoManager _manager; private Point2D.Double[] _realCoords = new Point2D.Double[0]; private Point2D.Double[] _realCenters = new Point2D.Double[0]; private double _scaleFactor = 1.0; private Point2D.Double _offsetPanel = new Point2D.Double(); private Point2D.Double _offsetRNA = new Point2D.Double(); private double _offX; private double _offY; private ControleurBlinkingThread _blink; private BaseList _selectedBases = new BaseList("selection"); private ArrayList<ModeleBase> _backupSelection = new ArrayList<ModeleBase>(); private Integer _nearestBase = null; private Point2D.Double _lastSelectedCoord = new Point2D.Double(0.0,0.0); private Point2D.Double _linkOrigin = null; private Point2D.Double _linkDestination = null; private Rectangle _selectionRectangle = null; private boolean _highlightAnnotation = false; private int _titleHeight; private Dimension _border = new Dimension(0,0); private boolean _drawBBox = false; private boolean _drawBorder = false; // private Point _positionRelativeSouris; private Point _translation; private boolean _horsCadre; private boolean _premierAffichage; private ControleurInterpolator _interpolator; /** * If comparison mode is TRUE (ON), then the application will be used to * display a super-structure resulting on an RNA secondary structure * comparison. Else, the application is used by default. */ private VueMenu _popup = new VueMenu(this); private VueUI _UI = new VueUI(this); private TextAnnotation _selectedAnnotation; /** * Creates an RNA 2D panel with initially displays the empty structure. * * @throws ExceptionNonEqualLength * */ public VARNAPanel() throws ExceptionNonEqualLength { this("", "", RNA.DRAW_MODE_RADIATE); } /** * Creates an RNA 2D panel, and creates and displays an RNA coupled with its * secondary structure formatted as a well-balanced parenthesis with dots * word (DBN format). * * @param seq * The raw nucleotide sequence * @param str * The secondary structure in DBN format * @throws ExceptionNonEqualLength */ public VARNAPanel(String seq, String str) throws ExceptionNonEqualLength { this(seq, str, RNA.DRAW_MODE_RADIATE); } /** * Creates a VARNAPanel instance, and creates and displays an RNA coupled with its * secondary structure formatted as a well-balanced parenthesis with dots * word (DBN format). Allows the user to choose the drawing algorithm to be * used. * * @param seq * The raw nucleotide sequence * @param str * The secondary structure in DBN format * @param drawMode * The drawing mode * @throws ExceptionNonEqualLength * @see RNA#DRAW_MODE_RADIATE * @see RNA#DRAW_MODE_CIRCULAR * @see RNA#DRAW_MODE_NAVIEW */ public VARNAPanel(String seq, String str, int drawMode) throws ExceptionNonEqualLength { this(seq, str, drawMode, ""); } public VARNAPanel(Reader r) throws ExceptionNonEqualLength, ExceptionFileFormatOrSyntax { this(r, RNA.DRAW_MODE_RADIATE); } public VARNAPanel(Reader r, int drawMode) throws ExceptionNonEqualLength, ExceptionFileFormatOrSyntax { this(r, drawMode, ""); } public VARNAPanel(Reader r, int drawMode, String title) throws ExceptionNonEqualLength, ExceptionFileFormatOrSyntax { init(); drawRNA(r, drawMode); setTitle(title); } public void setOriginLink(Point2D.Double p) { _linkOrigin = (p); } public void setDestinationLink(Point2D.Double p) { _linkDestination = (p); } public void removeLink() { _linkOrigin = null; _linkDestination = null; } /** * Creates a VARNAPanel instance, and displays an RNA. * @param r The RNA to be displayed within this panel */ public VARNAPanel(RNA r){ showRNA(r); init(); } /** * Creates a VARNAPanel instance, and creates and displays an RNA coupled with its * secondary structure formatted as a well-balanced parenthesis with dots * word (DBN format). Allows the user to choose the drawing algorithm to be * used. Additionally, sets the panel's title. * * @param seq * The raw nucleotide sequence * @param str * The secondary structure in DBN format * @param drawMode * The drawing mode * @param title * The panel title * @throws ExceptionNonEqualLength * @see RNA#DRAW_MODE_CIRCULAR * @see RNA#DRAW_MODE_RADIATE * @see RNA#DRAW_MODE_NAVIEW */ public VARNAPanel(String seq, String str, int drawMode, String title) throws ExceptionNonEqualLength { drawRNA(seq, str, drawMode); init(); setTitle(title); //VARNASecDraw._vp = this; } public VARNAPanel(String seq1, String struct1, String seq2, String struct2, int drawMode, String title) { _conf._comparisonMode = true; drawRNA(seq1, struct1, seq2, struct2, drawMode); init(); setTitle(title); } private void init() { setBackground(VARNAConfig.DEFAULT_BACKGROUND_COLOR); _manager = new UndoManager(); _manager.setLimit(10000); _UI.addUndoableEditListener(_manager); _blink = new ControleurBlinkingThread(this, ControleurBlinkingThread.DEFAULT_FREQUENCY, 0, 1.0, 0.0, 0.2); _blink.start(); _premierAffichage = true; _translation = new Point(0, 0); _horsCadre = false; this.setFont(_conf._fontBasesGeneral); // ajout des controleurs au VARNAPanel ControleurClicMovement controleurClicMovement = new ControleurClicMovement( this); this.addMouseListener(controleurClicMovement); this.addMouseMotionListener(controleurClicMovement); this.addMouseWheelListener(new ControleurMolette(this)); ControleurDraggedMolette ctrlDraggedMolette = new ControleurDraggedMolette( this); this.addMouseMotionListener(ctrlDraggedMolette); this.addMouseListener(ctrlDraggedMolette); ControleurVARNAPanelKeys ctrlKey = new ControleurVARNAPanelKeys(this); this.addKeyListener(ctrlKey); this.addFocusListener(ctrlKey); _interpolator = new ControleurInterpolator(this); _interpolator.start(); } public void undo() { //System.out.println(_manager.getUndoOrRedoPresentationName()); _manager.undo(); } public void redo() { _manager.redo(); } /** * Sets the new style of the title font. * * @param newStyle * An int that describes the new font style ("PLAIN","BOLD", * "BOLDITALIC", or "ITALIC") */ public void setTitleFontStyle(int newStyle) { _conf._titleFont = _conf._titleFont.deriveFont(newStyle); updateTitleHeight(); } /** * Sets the new size of the title font. * * @param newSize * The new size of the title font */ public void setTitleFontSize(float newSize) { _conf._titleFont = _conf._titleFont.deriveFont(newSize); updateTitleHeight(); } /** * Sets the new font family to be used for the title. Available fonts are * system-specific, yet it seems that "Arial", "Dialog", and "MonoSpaced" * are almost always available. * * @param newFamily * New font family used for the title */ public void setTitleFontFamily(String newFamily) { _conf._titleFont = new Font(newFamily, _conf._titleFont.getStyle(), _conf._titleFont.getSize()); updateTitleHeight(); } /** * Sets the color to be used for the title. * * @param newColor * A color used to draw the title */ public void setTitleFontColor(Color newColor) { _conf._titleColor = newColor; updateTitleHeight(); } /** * Sets the font size for displaying bases * * @param size * Font size for base caption */ public void setBaseFontSize(Float size) { _conf._fontBasesGeneral = _conf._fontBasesGeneral.deriveFont(size); } /** * Sets the font size for displaying base numbers * * @param size * Font size for base caption */ public void setNumbersFontSize(Float size) { _conf._numbersFont = _conf._numbersFont.deriveFont(size); } /** * Sets the font style for displaying bases * * @param style * An int that describes the new font style ("PLAIN","BOLD", * "BOLDITALIC", or "ITALIC") */ public void setBaseFontStyle(int style) { _conf._fontBasesGeneral = _conf._fontBasesGeneral.deriveFont(style); } private void updateTitleHeight() { if (!getTitle().equals("")) { _titleHeight = (int) (_conf._titleFont.getSize() * 1.5); } else { _titleHeight = 0; } if (_translation.x==0) {_translation.y = (int) (-getTitleHeight() / 2.0);} } /** * Sets the panel's title, giving a short description of the RNA secondary * structure. * * @param title * The new title */ public void setTitle(String title) { _RNA.setName(title); _conf._title = title; updateTitleHeight(); } /** * Sets the distance between consecutive base numbers. Please notice that : * <ul> * <li>The first and last base are always numbered</li> * <li>The numbering is based on the base numbers, not on the indices. So * base numbers may appear more frequently than expected if bases are * skipped</li> * <li>The periodicity is measured starting from 0. This means that for a * period of 10 and bases numbered from 1 to 52, the base numbers * [1,10,20,30,40,50,52] will be drawn.</li> * </ul> * * @param n * New numbering period */ public void setNumPeriod(int n) { _conf._numPeriod = n; } /** * Returns the current numbering period. Please notice that : * <ul> * <li>The first and last base are always numbered</li> * <li>The numbering is based on the base numbers, not on the indices. So * base numbers may appear more frequently than expected if bases are * skipped</li> * <li>The periodicity is measured starting from 0. This means that for a * period of 10 and bases numbered from 1 to 52, the base numbers * [1,10,20,30,40,50,52] will be drawn.</li> * </ul> * * @return Current numbering period */ public int getNumPeriod() { return _conf._numPeriod; } private void setAutoFit(boolean fit) { _conf._autoFit = fit; repaint(); } public void lockScrolling() { setAutoFit(false); setAutoCenter(false); } public void unlockScrolling() { setAutoFit(true); setAutoCenter(true); } private void drawStringOutline(VueVARNAGraphics g2D,String res, double x, double y, double margin) { Dimension d = g2D.getStringDimension(res); x -= (double) d.width / 2.0; y += (double) d.height / 2.0; g2D.setColor(Color.GRAY); g2D.setDashedStroke(); g2D.drawRect((x-margin), (y - d.height-margin), (d.width+2.0*margin), (d.height+2.0*margin)); } private void drawSymbol(VueVARNAGraphics g2D,double posx, double posy, double normx, double normy, double radius, boolean isCIS, ModeleBP.Edge e) { switch (e) { case WATSON_CRICK: if (isCIS) { g2D.fillCircle( (posx - (radius) / 2.0), (posy - (radius) / 2.0), radius); } else { Color bck = g2D.getColor(); g2D.setColor(Color.white); g2D.fillCircle( posx - (radius) / 2.0, (posy - (radius) / 2.0), (radius)); g2D.setColor(bck); g2D.drawCircle( (posx - (radius) / 2.0), (posy - (radius) / 2.0), (radius)); } break; case HOOGSTEEN: { GeneralPath p2 = new GeneralPath(); p2.moveTo((float) (posx - radius * normx / 2.0 - radius * normy / 2.0), (float) (posy - radius * normy / 2.0 + radius * normx / 2.0)); p2.lineTo((float) (posx + radius * normx / 2.0 - radius * normy / 2.0), (float) (posy + radius * normy / 2.0 + radius * normx / 2.0)); p2.lineTo((float) (posx + radius * normx / 2.0 + radius * normy / 2.0), (float) (posy + radius * normy / 2.0 - radius * normx / 2.0)); p2.lineTo((float) (posx - radius * normx / 2.0 + radius * normy / 2.0), (float) (posy - radius * normy / 2.0 - radius * normx / 2.0)); p2.closePath(); if (isCIS) { g2D.fill(p2); } else { Color bck = g2D.getColor(); g2D.setColor(Color.white); g2D.fill(p2); g2D.setColor(bck); g2D.draw(p2); } } break; case SUGAR: { double ix = radius * normx / 2.0; double iy = radius * normy / 2.0; double jx = radius * normy / 2.0; double jy = -radius * normx / 2.0; GeneralPath p2 = new GeneralPath(); p2.moveTo((float) (posx - ix + jx), (float) (posy - iy + jy)); p2.lineTo((float) (posx + ix + jx), (float) (posy + iy + jy)); p2.lineTo((float) (posx - jx), (float) (posy - jy)); p2.closePath(); if (isCIS) { g2D.fill(p2); } else { Color bck = g2D.getColor(); g2D.setColor(Color.white); g2D.fill(p2); g2D.setColor(bck); g2D.draw(p2); } } break; } } private void drawBasePair(VueVARNAGraphics g2D,Point2D.Double orig, Point2D.Double dest, ModeleBP style, double newRadius) { double dx = dest.x - orig.x; double dy = dest.y - orig.y; double dist = Math.sqrt((dest.x - orig.x) * (dest.x - orig.x) + (dest.y - orig.y) * (dest.y - orig.y)); dx /= dist; dy /= dist; double nx = -dy; double ny = dx; orig = new Point2D.Double(orig.x+newRadius*dx,orig.y+newRadius*dy); dest = new Point2D.Double(dest.x-newRadius*dx,dest.y-newRadius*dy); if (_conf._mainBPStyle == VARNAConfig.BP_STYLE.BP_STYLE_LW) { double radiusCircle = ((RNA.BASE_PAIR_DISTANCE - _RNA.BASE_RADIUS) / 5.0) * this._scaleFactor; if (style.isCanonical()) { if (style.isCanonicalGC()) { if ((orig.x != dest.x) || (orig.y != dest.y)) { nx *= this._scaleFactor * _RNA.BASE_RADIUS / 4.0; ny *= this._scaleFactor * _RNA.BASE_RADIUS / 4.0; g2D.drawLine( (orig.x + nx), (orig.y + ny), (dest.x + nx), (dest.y + ny)); g2D.drawLine( (orig.x - nx), (orig.y - ny), (dest.x - nx), (dest.y - ny)); } } else if (style.isCanonicalAU()){ g2D.drawLine(orig.x, orig.y, dest.x, dest.y); } else if (style.isWobbleUG()){ double cx = (dest.x + orig.x) / 2.0; double cy = (dest.y + orig.y) / 2.0; g2D.drawLine( orig.x, orig.y, dest.x, dest.y); drawSymbol(g2D, cx, cy, nx, ny, radiusCircle, false, ModeleBP.Edge.WATSON_CRICK); } else { double cx = (dest.x + orig.x) / 2.0; double cy = (dest.y + orig.y) / 2.0; g2D.drawLine( orig.x, orig.y, dest.x, dest.y); drawSymbol(g2D, cx, cy, nx, ny, radiusCircle, style .isCIS(), style.getEdgePartner5()); } } else { ModeleBP.Edge p1 = style.getEdgePartner5(); ModeleBP.Edge p2 = style.getEdgePartner3(); double cx = (dest.x + orig.x) / 2.0; double cy = (dest.y + orig.y) / 2.0; g2D.drawLine( orig.x, orig.y,dest.x, dest.y); if (p1 == p2) { drawSymbol(g2D, cx, cy, nx, ny, radiusCircle, style .isCIS(), p1); } else { double vdx = (dest.x - orig.x); double vdy = (dest.y - orig.y); vdx /= 6.0; vdy /= 6.0; drawSymbol(g2D, cx + vdx, cy + vdy, nx, ny, radiusCircle, style.isCIS(), p2); drawSymbol(g2D, cx - vdx, cy - vdy, nx, ny, radiusCircle, style.isCIS(), p1); } } } else if (_conf._mainBPStyle == VARNAConfig.BP_STYLE.BP_STYLE_SIMPLE) { g2D.drawLine( orig.x, orig.y,dest.x, dest.y); } else if (_conf._mainBPStyle == VARNAConfig.BP_STYLE.BP_STYLE_RNAVIZ) { double xcenter = (orig.x + dest.x) / 2.0; double ycenter = (orig.y + dest.y) / 2.0; double radius = Math.max(4.0 * this._scaleFactor, 1.0); g2D.fillCircle( (xcenter - radius), (ycenter - radius), (2.0 * radius)); } } private Color getHighlightedVersion(Color c1, Color c2) { int r1 = c1.getRed(); int g1 = c1.getGreen(); int b1 = c1.getBlue(); int r2 = c2.getRed(); int g2 = c2.getGreen(); int b2 = c2.getBlue(); double val = _blink.getVal(); int nr = Math.max(0, Math.min((int) ((r1 * val + r2 * (1.0 - val))), 255)); int ng = Math.max(0, Math.min((int) ((g1 * val + g2 * (1.0 - val))), 255)); int nb = Math.max(0, Math.min((int) ((b1 * val + b2 * (1.0 - val))), 255)); return new Color(nr, ng, nb); } private Color highlightFilter(int index, Color initialColor, Color c1, Color c2) { if (_selectedBases.contains(_RNA.getBaseAt(index))) { return getHighlightedVersion(c1, c2); } else return initialColor; } private Point2D.Double computeExcentricUnitVector(int i,Point2D.Double[] points,Point2D.Double[] centers) { double dist = points[i].distance(centers[i]); Point2D.Double byCenter = new Point2D.Double((points[i].x - centers[i].x)/dist,(points[i].y - centers[i].y)/dist); if ((i>0)&&(i<points.length-1)) { Point2D.Double p0 = points[i-1]; Point2D.Double p1 = points[i]; Point2D.Double p2 = points[i+1]; double dist1 = p2.distance(p1); Point2D.Double v1 = new Point2D.Double((p2.x-p1.x)/dist1,(p2.y-p1.y)/dist1); Point2D.Double vn1 = new Point2D.Double(v1.y,-v1.x); double dist2 = p1.distance(p0); Point2D.Double v2 = new Point2D.Double((p1.x-p0.x)/dist2,(p1.y-p0.y)/dist2); Point2D.Double vn2 = new Point2D.Double(v2.y,-v2.x); Point2D.Double vn = new Point2D.Double((vn1.x+vn2.x)/2.0,(vn1.y+vn2.y)/2.0); double D = vn.distance(new Point2D.Double(0.0,0.0)); vn.x/= D; vn.y/= D; if (byCenter.x*vn.x+byCenter.y*vn.y<0) { vn.x = -vn.x; vn.y = -vn.y; } return vn; } else { return byCenter; } } private void drawBase(VueVARNAGraphics g2D,int i, Point2D.Double[] points, Point2D.Double[] centers, double newRadius) { Point2D.Double p = points[i]; ModeleBase mb = _RNA.get_listeBases().get(i); g2D.setFont(_conf._fontBasesGeneral); Color baseInnerColor = highlightFilter(i, _RNA.getBaseInnerColor(i, _conf), Color.white, _RNA.getBaseInnerColor(i,_conf)); Color baseOuterColor = highlightFilter(i, _RNA.getBaseOuterColor(i, _conf), _RNA.getBaseOuterColor(i, _conf), Color.white); Color baseNameColor = highlightFilter(i, _RNA.getBaseNameColor(i, _conf), _RNA.getBaseNameColor(i, _conf),Color.white); if (mb instanceof ModeleBaseNucleotide) { ModeleBaseNucleotide mbn = (ModeleBaseNucleotide) mb; String res = mbn.get_c(); if (_hoveredBase== mb) { g2D.setColor(_conf._hoverColor); g2D.fillCircle(p.getX()-1.5*newRadius, p.getY()-1.5*newRadius,3.0 * newRadius); g2D.setColor(_conf._hoverColor.darker()); g2D.drawCircle(p.getX()-1.5*newRadius, p.getY()-1.5*newRadius,3.0 * newRadius); g2D.setPlainStroke(); } if (_conf._fillBase) { // Filling inner circle g2D.setColor(baseInnerColor); g2D.fillCircle(p.getX()-newRadius, p.getY()-newRadius,2.0 * newRadius); } if (_conf._drawOutlineBase) { // Drawing outline g2D.setColor(baseOuterColor); g2D.setStrokeThickness(_conf._baseThickness * _scaleFactor); g2D.drawCircle(p.getX()-newRadius, p.getY()-newRadius,2.0 * newRadius); } // Drawing label g2D.setColor(baseNameColor); g2D.drawStringCentered(String.valueOf(res), p.getX(), p.getY()); } else if (mb instanceof ModeleBasesComparison) { ModeleBasesComparison mbc = (ModeleBasesComparison) mb; // On lui donne l'aspect voulue (on a un trait droit) g2D.setPlainStroke(); // On doit avoir un trait droit, sans arrondit g2D.setStrokeThickness(_conf._baseThickness * _scaleFactor); // On dessine l'étiquette, rectangle aux bords arrondies. g2D.setColor(baseInnerColor); g2D.fillRoundRect((p.getX() - newRadius), (p.getY() - newRadius), (3.0 * newRadius), (2.0 * newRadius), 10*_scaleFactor, 10*_scaleFactor); /* Dessin du rectangle exterieur (bords) */ g2D.setColor(baseOuterColor); g2D.drawRoundRect((p.getX() - newRadius), (p.getY() - newRadius), (3 * newRadius), (2 * newRadius), 10*_scaleFactor, 10*_scaleFactor); // On le dessine au centre de l'étiquette. g2D.drawLine((p.getX() + (newRadius) / 2.0), (p.getY() + newRadius)-1, (p.getX() + (newRadius / 2.0)), (p.getY() - newRadius)+1); /* Dessin du nom de la base (A,C,G,U,etc...) */ // On créer le texte des étiquettes String label1 = String.valueOf(mbc.get_base1()); String label2 = String.valueOf(mbc.get_base2()); // On leur donne une couleur g2D.setColor(getRNA().get_listeBases().get(i).getStyleBase() .get_base_name_color()); // Et on les dessine. g2D.drawStringCentered( label1, p.getX() - (newRadius * 0.15), p.getY()); g2D.drawStringCentered( label2, p.getX() + (newRadius * 1.2), p.getY()); } // Drawing base number if (_RNA.isNumberDrawn(mb,getNumPeriod())) { Point2D.Double vn = computeExcentricUnitVector(i,points,centers); g2D.setColor(mb.getStyleBase().get_base_number_color()); g2D.setFont(_conf._numbersFont); double factorMin = Math.min(.5, _conf._distNumbers); double factorMax = Math.min(_conf._distNumbers-1.5, _conf._distNumbers); g2D.drawLine(p.x + vn.x*((1+factorMin)*newRadius), p.y + vn.y*((1+factorMin)*newRadius), p.x + vn.x*((1+factorMax)*newRadius), p.y + vn.y*((1+factorMax)*newRadius)); g2D.drawStringCentered("" + (mb.getBaseNumber()), p.x + vn.x*((1+_conf._distNumbers)*newRadius), p.y + vn.y*((1+_conf._distNumbers)*newRadius)); } } void drawChemProbAnnotation(VueVARNAGraphics g2D, ChemProbAnnotation cpa, Point2D.Double anchor, double scaleFactor) { g2D.setColor(cpa.getColor()); g2D.setStrokeThickness(RNA.CHEM_PROB_ARROW_THICKNESS * _scaleFactor*cpa.getIntensity()); g2D.setPlainStroke(); Point2D.Double v = cpa.getDirVector(); Point2D.Double vn = cpa.getNormalVector(); Point2D.Double base = new Point2D.Double((anchor.x+_RNA.CHEM_PROB_DIST*scaleFactor*v.x),(anchor.y+_RNA.CHEM_PROB_DIST*scaleFactor*v.y)); Point2D.Double edge = new Point2D.Double((base.x+_RNA.CHEM_PROB_BASE_LENGTH*cpa.getIntensity()*scaleFactor*v.x),(base.y+_RNA.CHEM_PROB_BASE_LENGTH*cpa.getIntensity()*scaleFactor*v.y)); switch (cpa.getType()) { case ARROW_TYPE: { Point2D.Double arrowTip1 = new Point2D.Double((base.x+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_ARROW_WIDTH*vn.x+_RNA.CHEM_PROB_ARROW_HEIGHT*v.x)), (base.y+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_ARROW_WIDTH*vn.y+_RNA.CHEM_PROB_ARROW_HEIGHT*v.y))); Point2D.Double arrowTip2 = new Point2D.Double((base.x+cpa.getIntensity()*scaleFactor*(-_RNA.CHEM_PROB_ARROW_WIDTH*vn.x+_RNA.CHEM_PROB_ARROW_HEIGHT*v.x)), (base.y+cpa.getIntensity()*scaleFactor*(-_RNA.CHEM_PROB_ARROW_WIDTH*vn.y+_RNA.CHEM_PROB_ARROW_HEIGHT*v.y))); g2D.drawLine(base.x,base.y,edge.x,edge.y); g2D.drawLine(base.x,base.y,arrowTip1.x,arrowTip1.y); g2D.drawLine(base.x,base.y,arrowTip2.x,arrowTip2.y); } break; case PIN_TYPE: { Point2D.Double side1 = new Point2D.Double((edge.x-cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*v.x)), (edge.y-cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*v.y))); Point2D.Double side2 = new Point2D.Double((edge.x-cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*vn.x)), (edge.y-cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*vn.y))); Point2D.Double side3 = new Point2D.Double((edge.x+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*v.x)), (edge.y+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*v.y))); Point2D.Double side4 = new Point2D.Double((edge.x+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*vn.x)), (edge.y+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_PIN_SEMIDIAG*vn.y))); GeneralPath p2 = new GeneralPath(); p2.moveTo((float)side1.x,(float)side1.y); p2.lineTo((float)side2.x,(float)side2.y); p2.lineTo((float)side3.x,(float)side3.y); p2.lineTo((float)side4.x,(float)side4.y); p2.closePath(); g2D.fill(p2); g2D.drawLine(base.x,base.y,edge.x,edge.y); } break; case TRIANGLE_TYPE: { Point2D.Double arrowTip1 = new Point2D.Double((edge.x+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_TRIANGLE_WIDTH*vn.x)), (edge.y+cpa.getIntensity()*scaleFactor*(_RNA.CHEM_PROB_TRIANGLE_WIDTH*vn.y))); Point2D.Double arrowTip2 = new Point2D.Double((edge.x+cpa.getIntensity()*scaleFactor*(-_RNA.CHEM_PROB_TRIANGLE_WIDTH*vn.x)), (edge.y+cpa.getIntensity()*scaleFactor*(-_RNA.CHEM_PROB_TRIANGLE_WIDTH*vn.y))); GeneralPath p2 = new GeneralPath(); p2.moveTo((float)base.x,(float)base.y); p2.lineTo((float)arrowTip1.x,(float)arrowTip1.y); p2.lineTo((float)arrowTip2.x,(float)arrowTip2.y); p2.closePath(); g2D.fill(p2); } break; case DOT_TYPE: { Double radius = scaleFactor*_RNA.CHEM_PROB_DOT_RADIUS*cpa.getIntensity(); Point2D.Double center = new Point2D.Double((base.x+radius*v.x),(base.y+radius*v.y)); g2D.fillCircle((center.x-radius), (center.y-radius), (2*radius)); } break; } } Point2D.Double buildCaptionPosition(ModeleBase mb, double scaleFactor, double heightEstimate) { double radius = 2.0; if (_RNA.isNumberDrawn(mb,getNumPeriod())) { radius += _conf._distNumbers; } Point2D.Double center = mb.getCenter(); Point2D.Double p = mb.getCoords(); double realDistance = _RNA.BASE_RADIUS*radius + heightEstimate; return new Point2D.Double(center.getX() + (p.getX() - center.getX()) * ((p.distance(center) + realDistance) / p .distance(center)), center.getY() + (p.getY() - center.getY()) * ((p.distance(center) + realDistance) / p .distance(center)) ); } private void renderAnnotations(VueVARNAGraphics g2D, double offX, double offY, double rnaBBoxX,double rnaBBoxY, double scaleFactor) { for (TextAnnotation textAnnotation : _RNA.getAnnotations()) { g2D.setColor(textAnnotation.getColor()); g2D.setFont(textAnnotation.getFont().deriveFont((float)(2.0*textAnnotation.getFont().getSize()*scaleFactor))); Point2D.Double position = textAnnotation.getCenterPosition(); if (textAnnotation.getType()==TextAnnotation.BASE) { ModeleBase mb = (ModeleBase) textAnnotation.getAncrage(); double fontHeight = Math.ceil(textAnnotation.getFont().getSize()); position = buildCaptionPosition(mb,scaleFactor,fontHeight); } position = transformCoord(position,offX, offY, rnaBBoxX,rnaBBoxY, scaleFactor); g2D.drawStringCentered(textAnnotation.getTexte(), position.x, position.y); if ((_selectedAnnotation == textAnnotation)&&(_highlightAnnotation)) { drawStringOutline(g2D, textAnnotation.getTexte(), position.x, position.y, 5); } } for (ChemProbAnnotation cpa : _RNA.getChemProbAnnotations()) { Point2D.Double anchor = transformCoord(cpa.getAnchorPosition(),offX, offY, rnaBBoxX,rnaBBoxY, scaleFactor); drawChemProbAnnotation(g2D, cpa,anchor, scaleFactor); } } public Rectangle2D.Double getExtendedRNABBox() { // We get the logical bounding box Rectangle2D.Double rnabbox = _RNA.getBBox(); rnabbox.y -= _conf._distNumbers*_RNA.BASE_RADIUS; rnabbox.height += 2.0*_conf._distNumbers*_RNA.BASE_RADIUS; rnabbox.x -= _conf._distNumbers*_RNA.BASE_RADIUS; rnabbox.width += 2.0*_conf._distNumbers*_RNA.BASE_RADIUS; if (_RNA.hasVirtualLoops()) { rnabbox.y -= RNA.VIRTUAL_LOOP_RADIUS; rnabbox.height += 2.0*RNA.VIRTUAL_LOOP_RADIUS; rnabbox.x -= RNA.VIRTUAL_LOOP_RADIUS; rnabbox.width += 2.0*RNA.VIRTUAL_LOOP_RADIUS; } return rnabbox; } public void drawBackbone(VueVARNAGraphics g2D, Point2D.Double[] newCoords, double newRadius) { // Drawing backbone if (getDrawBackbone()) { g2D.setStrokeThickness(1.5 * _scaleFactor); g2D.setColor(_conf._backboneColor); for (int i = 1; i < _RNA.get_listeBases().size(); i++) { Point2D.Double p1 = newCoords[i-1]; Point2D.Double p2 = newCoords[i]; double dist = p1.distance(p2); boolean discontinuous = (_RNA.getBaseNumber(i)-_RNA.getBaseNumber(i-1)!=1); int a = _RNA.getBaseAt(i-1).getElementStructure(); int b = _RNA.getBaseAt(i).getElementStructure(); boolean consecutive = (a==i)&&(b==i-1); if ((dist>0)){ Point2D.Double vbp = new Point2D.Double(); vbp.x = (p2.x-p1.x)/dist; vbp.y = (p2.y-p1.y)/dist; if (!discontinuous) { g2D.setPlainStroke(); } else { g2D.setDashedStroke(); } if (consecutive && (_RNA.getDrawMode()!=RNA.DRAW_MODE_LINEAR) && (_RNA.getDrawMode()!=RNA.DRAW_MODE_CIRCULAR)) { int dir = 0; if (i+1<newCoords.length) {dir = (_RNA.testDirectionality(i-1,i,i+1)?-1:1);} else if (i-2>=0) {dir = (_RNA.testDirectionality(i-2,i-1,i)?-1:1);} Point2D.Double vn = new Point2D.Double(dir*vbp.y,-dir*vbp.x); Point2D.Double centerSeg = new Point2D.Double((p1.x+p2.x)/2.0,(p1.y+p2.y)/2.0); double distp1CenterSeq = p1.distance(centerSeg); double centerDist = Math.sqrt((RNA.VIRTUAL_LOOP_RADIUS*_scaleFactor*RNA.VIRTUAL_LOOP_RADIUS*_scaleFactor)-distp1CenterSeq*distp1CenterSeq); Point2D.Double centerLoop = new Point2D.Double(centerSeg.x+centerDist*vn.x,centerSeg.y+centerDist*vn.y); double radius = centerLoop.distance(p1); double a1 = 360.*(Math.atan2(-(p1.y-centerLoop.y),(p1.x-centerLoop.x)))/(2.*Math.PI); double a2 = 360.*(Math.atan2(-(p2.y-centerLoop.y),(p2.x-centerLoop.x)))/(2.*Math.PI); double angle = (a2-a1); if (-dir*angle<0){angle+= -dir*360.;} //if (angle<0.) angle += 360.; //angle = -dir*(360-dir*angle); g2D.drawArc(centerLoop.x+.8*newRadius*vn.x, centerLoop.y+.8*newRadius*vn.y, 2*radius, 2*radius, a1, angle); } else { g2D.drawLine( (newCoords[i - 1].x+newRadius*vbp.x), (newCoords[i - 1].y+newRadius*vbp.y), (newCoords[i].x-newRadius*vbp.x), (newCoords[i].y-newRadius*vbp.y)); } } } } } public Point2D.Double logicToPanel(Point2D.Double logicPoint) { return new Point2D.Double( _offX + (_scaleFactor * (logicPoint.x - _offsetRNA.x)), _offY + (_scaleFactor * (logicPoint.y - _offsetRNA.y))); } private void renderRNA(VueVARNAGraphics g2D, Rectangle2D.Double bbox) { if (_RNA.get_listeBases().size() != 0) { //_conf._autoCenter = (_RNA.get_drawMode() != RNA.DRAW_MODE_LINEAR); Rectangle2D.Double rnabbox = getExtendedRNABBox(); // Then compute an estimate of the scaling factor if (_conf._autoFit) { setScaleFactor(Math.min((double) bbox.width / (double) rnabbox.width, (double) bbox.height / (double) rnabbox.height)); } // Use it to get an estimate of the font size for numbers ... float newFontSize = Math.max(1, (int) ((1.7 * _RNA.BASE_RADIUS) * _scaleFactor)); // ... and increase bounding box accordingly rnabbox.y -= newFontSize; rnabbox.height += newFontSize; if (_conf._drawColorMap) { rnabbox.height += getColorMapHeight(); } rnabbox.x -= newFontSize; rnabbox.width += newFontSize; // Now, compute the final scaling factor and corresponding font size if (_conf._autoFit) { setScaleFactor(Math.min((double) bbox.width / (double) rnabbox.width, (double) bbox.height / (double) rnabbox.height)); } newFontSize = Math.max(1, (int) ((1.7 * _RNA.BASE_RADIUS) * _scaleFactor)); double newRadius = Math.max(1.0, (_scaleFactor * _RNA.BASE_RADIUS)); setBaseFontSize(newFontSize); setNumbersFontSize(newFontSize); if (_conf._autoCenter) { _offX = bbox.x; _offY = bbox.y; _offX = (bbox.x + (bbox.width - Math.round(rnabbox.width * _scaleFactor)) / 2.0); _offY = (bbox.y + (bbox.height - Math.round(rnabbox.height * _scaleFactor)) / 2.0); _offsetPanel = new Point2D.Double(_offX, _offY); _offsetRNA = new Point2D.Double(rnabbox.x, rnabbox.y); } // Re-scaling once and for all Point2D.Double[] newCoords = new Point2D.Double[_RNA .get_listeBases().size()]; Point2D.Double[] newCenters = new Point2D.Double[_RNA .get_listeBases().size()]; for (int i = 0; i < _RNA.get_listeBases().size(); i++) { ModeleBase mb = _RNA.getBaseAt(i); newCoords[i] = new Point2D.Double( _offX + (_scaleFactor * (mb.getCoords().x - _offsetRNA.x)), _offY + (_scaleFactor * (mb.getCoords().y - _offsetRNA.y))); Point2D.Double centerBck = _RNA.getCenter(i); // si la base est dans un angle entre une boucle et une helice if (_RNA.get_drawMode() == RNA.DRAW_MODE_NAVIEW || _RNA.get_drawMode() == RNA.DRAW_MODE_RADIATE) { if ((mb.getElementStructure() != -1) && i < _RNA.get_listeBases().size() - 1 && i > 1) { ModeleBase b1 = _RNA.get_listeBases().get(i - 1); ModeleBase b2 = _RNA.get_listeBases().get(i + 1); int j1 = b1.getElementStructure(); int j2 = b2.getElementStructure(); if ((j1==-1)^(j2==-1)) { // alors la position du nombre associé doit etre décalé Point2D.Double a1 = b1.getCoords(); Point2D.Double a2 = b2.getCoords(); Point2D.Double c1 = b1.getCenter(); Point2D.Double c2 = b2.getCenter(); centerBck.x = mb.getCoords().x + (c1.x-a1.x)/c1.distance(a1)+(c2.x-a2.x)/c2.distance(a2); centerBck.y = mb.getCoords().y + (c1.y-a1.y)/c1.distance(a1)+(c2.y-a2.y)/c2.distance(a2); } } } newCenters[i] = new Point2D.Double( _offX + (_scaleFactor * (centerBck.x - _offsetRNA.x)), _offY + (_scaleFactor * (centerBck.y - _offsetRNA.y))); } // Keep track of coordinates for mouse interactions _realCoords = newCoords; _realCenters = newCenters; g2D.setStrokeThickness(1.5 * _scaleFactor); g2D.setPlainStroke(); g2D.setFont(_conf._fontBasesGeneral); // Drawing region highlights Annotation drawRegionHighlightsAnnotation(g2D, _realCoords,_realCenters,_scaleFactor); drawBackbone(g2D, newCoords,newRadius); // Drawing base-pairs double distance, coef; // pour chaque base for (int i = 0; i < _RNA.get_listeBases().size(); i++) { int j = _RNA.get_listeBases().get(i).getElementStructure(); // si c'est une parenthese ouvrante (premiere base du // couple) if (j > i) { ModeleBP msbp = _RNA.get_listeBases().get(i) .getStyleBP(); //System.err.println(msbp); if (msbp.isCanonical() || _conf._drawnNonCanonicalBP) { if (_RNA.get_drawMode() == RNA.DRAW_MODE_LINEAR) { g2D.setStrokeThickness(_RNA .getBasePairThickness(msbp, _conf) * 2.0 * _scaleFactor * _conf._bpThickness); } else { g2D.setStrokeThickness(_RNA.getBasePairThickness(msbp, _conf) * 1.5 * _scaleFactor); } g2D.setColor(_RNA.getBasePairColor(msbp, _conf)); if (_RNA.get_drawMode() == RNA.DRAW_MODE_LINEAR) { if (j - i == 1) coef = getBPHeightIncrement() * 1.75; else coef = getBPHeightIncrement(); distance = newCoords[j].x - newCoords[i].x; g2D.drawArc((newCoords[j].x + newCoords[i].x)/2., newCoords[j].y-_scaleFactor * _RNA.BASE_RADIUS / 2.0, (distance), (distance * coef), 0, 180); } else { drawBasePair(g2D, newCoords[i], newCoords[j], msbp, newRadius); } } } } // Liaisons additionelles (non planaires) if (_conf._drawnNonPlanarBP) { ArrayList<ModeleBP> bpaux = _RNA.getStructureAux(); for (int k = 0; k < bpaux.size(); k++) { ModeleBP bp = bpaux.get(k); if (bp.isCanonical() || _conf._drawnNonCanonicalBP) { int i = bp.getPartner5().getIndex(); int j = bp.getPartner3().getIndex(); if (_RNA.get_drawMode() == RNA.DRAW_MODE_LINEAR) { g2D.setStrokeThickness(_RNA .getBasePairThickness(bp, _conf) * 2.5 * _scaleFactor * _conf._bpThickness); g2D.setPlainStroke(); } else { g2D.setStrokeThickness(_RNA.getBasePairThickness(bp, _conf) * 1.5 * _scaleFactor); g2D.setPlainStroke(); } g2D.setColor(_RNA.getBasePairColor(bp, _conf)); if (j > i) { if (_RNA.get_drawMode() == RNA.DRAW_MODE_LINEAR ) { if (j - i == 1) coef = getBPHeightIncrement() * 1.75; else coef = getBPHeightIncrement(); distance = newCoords[j].x - newCoords[i].x; g2D.drawArc((newCoords[j].x + newCoords[i].x)/2., newCoords[j].y-_scaleFactor * _RNA.BASE_RADIUS / 2.0, (distance), (distance * coef), 0, 180); } else { drawBasePair(g2D, newCoords[i], newCoords[j], bp, newRadius); } } } } } // Drawing bases g2D.setPlainStroke(); for (int i = 0; i < Math.min(_RNA.get_listeBases().size(), newCoords.length); i++) { /*if (mb instanceof ModeleBasesComparison) { ModeleBasesComparison mbc = (ModeleBasesComparison)mb; drawBaseComparison(g2D, i, mbc.get_base1(), mbc.get_base2(), newCoords[i], newCenters[i], newRadius); } else if (mb instanceof ModeleBaseNucleotide)*/ { drawBase(g2D, i, newCoords, newCenters, newRadius); } } // Drawing bbox if (_debug || _drawBBox) { g2D.setColor(Color.RED); g2D.setDashedStroke(); g2D.drawRect(_offX, _offY, (_scaleFactor * rnabbox.width)-1, (_scaleFactor * rnabbox.height)-1); } // Draw color map if (_conf._drawColorMap) { drawColorMap(g2D, _scaleFactor,rnabbox); } if (_debug || _drawBBox) { g2D.setColor(Color.GRAY); g2D.setDashedStroke(); g2D.drawRect(0,0, getWidth()-1, getHeight()-getTitleHeight()-1); } // Draw annotations renderAnnotations(g2D, _offX,_offY,_offsetRNA.x,_offsetRNA.y,_scaleFactor); // Draw additional debug shape if (_RNA._debugShape!=null) { Color c = new Color(255,0,0,50); g2D.setColor(c); AffineTransform at = new AffineTransform(); at.translate(_offX - _scaleFactor *rnabbox.x, _offY - _scaleFactor *rnabbox.y); at.scale(_scaleFactor, _scaleFactor); Shape s = at.createTransformedShape(_RNA._debugShape); if (s instanceof GeneralPath) { g2D.fill((GeneralPath)s); } } } } public ModeleBase getBaseAt(Point2D.Double po) { ModeleBase mb = null; Point2D.Double p = panelToLogicPoint(po); double dist = Double.MAX_VALUE; for(ModeleBase tmp : _RNA.get_listeBases()) { double ndist = tmp.getCoords().distance(p); if (dist > ndist) { mb = tmp; dist = ndist; } } return mb; } public void setColorMapValues(Double[] values){ _RNA.setColorMapValues(values, _conf._cm,true); _conf._drawColorMap = true; repaint(); } public void setColorMapMaxValue(double d) { _conf._cm.setMaxValue(d); } public void setColorMapMinValue(double d) { _conf._cm.setMinValue(d); } public ModeleColorMap getColorMap(){ return _conf._cm; } public void setColorMap(ModeleColorMap cm){ _RNA.adaptColorMapToValues(cm); _conf._cm = cm; repaint(); } public void setColorMapCaption(String caption){ _conf._colorMapCaption = caption; repaint(); } public String getColorMapCaption(){ return _conf._colorMapCaption; } public void drawColorMap(boolean draw){ _conf._drawColorMap = draw; } private double getColorMapHeight() { double result = VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE+_conf._colorMapHeight; if (!_conf._colorMapCaption.equals("")) result += VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE; return result; } private void drawColorMap(VueVARNAGraphics g2D, double scaleFactor, Rectangle2D.Double rnabbox) { double v1 = _conf._cm.getMinValue(); double v2 = _conf._cm.getMaxValue(); double x,y; g2D.setPlainStroke(); double xSpaceAvail = 0; double ySpaceAvail = Math.min((getHeight()-rnabbox.height*scaleFactor-getTitleHeight())/2.0,scaleFactor*(_conf._colorMapHeight+VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE)); if ((int)ySpaceAvail==0) { xSpaceAvail = Math.min((getWidth()-rnabbox.width*scaleFactor)/2,scaleFactor*(_conf._colorMapWidth)+VARNAConfig.DEFAULT_COLOR_MAP_STRIPE_WIDTH); } double xBase = (xSpaceAvail+ _offX + scaleFactor*( rnabbox.width-_conf._colorMapWidth-_conf._colorMapXOffset )); double hcaption = VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE; double yBase = ( ySpaceAvail+ _offY + scaleFactor*(rnabbox.height - _conf._colorMapHeight - _conf._colorMapYOffset-hcaption)); for (int i=0;i<_conf._colorMapWidth;i++) { double ratio = (((double)i)/((double)_conf._colorMapWidth)); double val = v1+(v2-v1)*ratio; g2D.setColor(_conf._cm.getColorForValue(val)); x = (xBase + scaleFactor*i); y = yBase; g2D.fillRect(x, y, VARNAConfig.DEFAULT_COLOR_MAP_STRIPE_WIDTH, (scaleFactor*_conf._colorMapHeight)); } g2D.setColor(VARNAConfig.DEFAULT_COLOR_MAP_OUTLINE); g2D.drawRect(xBase, yBase, (VARNAConfig.DEFAULT_COLOR_MAP_STRIPE_WIDTH-1+scaleFactor*_conf._colorMapWidth), ((scaleFactor*_conf._colorMapHeight))); g2D.setFont(getFont().deriveFont((float) (scaleFactor*VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE))); g2D.setColor(VARNAConfig.DEFAULT_COLOR_MAP_FONT_COLOR); NumberFormat nf = NumberFormat.getInstance(); nf.setMaximumFractionDigits(2); nf.setMinimumFractionDigits(2); g2D.drawStringCentered(nf.format(_conf._cm.getMinValue()),xBase,yBase-scaleFactor*(VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE)/1.7); g2D.drawStringCentered(nf.format(_conf._cm.getMaxValue()), xBase+VARNAConfig.DEFAULT_COLOR_MAP_STRIPE_WIDTH+scaleFactor*_conf._colorMapWidth, yBase-scaleFactor*(VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE)/1.7); if (!_conf._colorMapCaption.equals("")) g2D.drawStringCentered(""+_conf._colorMapCaption,xBase+scaleFactor*_conf._colorMapWidth/2.0,yBase+scaleFactor*(VARNAConfig.DEFAULT_COLOR_MAP_FONT_SIZE/1.7+_conf._colorMapHeight)); } public Point2D.Double panelToLogicPoint(Point2D.Double p) { return new Point2D.Double(((p.x - getOffsetPanel().x) / getScaleFactor()) + getRNAOffset().x, ((p.y - getOffsetPanel().y) / getScaleFactor()) + getRNAOffset().y); } public Point2D.Double transformCoord(Point2D.Double coordDebut, double offX, double offY, double rnaBBoxX,double rnaBBoxY, double scaleFactor) { return new Point2D.Double( offX + (scaleFactor * (coordDebut.x - rnaBBoxX)), offY+ (scaleFactor * (coordDebut.y - rnaBBoxY))); } public void eraseSequence() { _RNA.eraseSequence(); } public Point2D.Double transformCoord(Point2D.Double coordDebut) { Rectangle2D.Double rnabbox = getExtendedRNABBox(); return new Point2D.Double( _offX + (_scaleFactor * (coordDebut.x - rnabbox.x)), _offY+ (_scaleFactor * (coordDebut.y - rnabbox.y))); } public void paintComponent(Graphics g) { paintComponent(g, false); } public void paintComponent(Graphics g, boolean transparentBackground) { if (_premierAffichage) { //_border = new Dimension(0, 0); _translation.x = 0; _translation.y = (int) (-getTitleHeight() / 2.0); _popup.buildPopupMenu(); this.add(_popup); _premierAffichage = false; } Graphics2D g2 = (Graphics2D) g; VueVARNAGraphics g2D = new SwingGraphics(g2); g2.setRenderingHint(RenderingHints.KEY_ANTIALIASING, RenderingHints.VALUE_ANTIALIAS_ON); //renderComponent(g2D,transparentBackground); this.removeAll(); super.paintComponent(g2); renderComponent(g2D, transparentBackground); if (isFocusOwner()) { g2.setStroke(new BasicStroke(1.5f)); g2.setColor(Color.decode("#C0C0C0")); g2.drawRect(0, 0, getWidth()-1, getHeight()-1); } /*PSExport e = new PSExport(); SecStrProducerGraphics export = new SecStrProducerGraphics(e); renderRNA(export, getExtendedRNABBox()); try { export.saveToDisk("./out.ps"); } catch (ExceptionWritingForbidden e1) { e1.printStackTrace(); }*/ } /** * Draws current RNA structure in a given Graphics "device". * * @param g2D * A graphical device * @param transparentBackground * Whether the background should be transparent, or drawn. */ public synchronized void renderComponent(VueVARNAGraphics g2D, boolean transparentBackground) { updateTitleHeight(); if (_debug || _drawBorder) { g2D.setColor(Color.BLACK); g2D.setPlainStroke(); g2D.drawRect(this.getLeftOffset(), this.getTopOffset(), this.getInnerWidth(), this.getInnerHeight()); } if (!transparentBackground) { super.setBackground(_conf._backgroundColor); } else { super.setBackground(new Color(0,0,0,120)); } if (getMinimumSize().height < getSize().height && getMinimumSize().width < getSize().width) { // Draw Title if (!getTitle().equals("")) { g2D.setColor(_conf._titleColor); g2D.setFont(_conf._titleFont); g2D.drawStringCentered(getTitle(), this.getWidth() / 2, this.getHeight() - getTitleHeight() / 2.0); } // Draw RNA renderRNA(g2D, getClip()); } if (_selectionRectangle!=null) { g2D.setColor(Color.BLACK); g2D.setDashedStroke(); g2D.drawRect(_selectionRectangle.x,_selectionRectangle.y,_selectionRectangle.width,_selectionRectangle.height); } if ((_linkOrigin != null) && (_linkDestination!=null)) { g2D.setColor(_conf._bondColor); g2D.setPlainStroke(); g2D.setStrokeThickness(4.0 * _scaleFactor); Point2D.Double linkOrigin = (_linkOrigin); Point2D.Double linkDestination = (_linkDestination); g2D.drawLine(linkOrigin.x,linkOrigin.y,linkDestination.x,linkDestination.y); for (int i: getSelection().getIndices()) drawBase(g2D, i, _realCoords, _realCenters, _scaleFactor*_RNA.BASE_RADIUS); } } public void drawRegionHighlightsAnnotation(VueVARNAGraphics g2D, Point2D.Double[] realCoords,Point2D.Double[] realCenters, double scaleFactor) { g2D.setStrokeThickness(2.0 * _scaleFactor); g2D.setPlainStroke(); for (HighlightRegionAnnotation r:_RNA.getHighlightRegion()) { GeneralPath s = r.getShape(realCoords,realCenters,scaleFactor); g2D.setColor(r.getFillColor()); g2D.fill(s); g2D.setColor(r.getOutlineColor()); g2D.draw(s); } } private Rectangle2D.Double getClip() { return new Rectangle2D.Double(this.getLeftOffset(), this.getTopOffset(), this.getInnerWidth(), this .getInnerHeight()); } /** * Returns the color used to draw backbone bounds. * * @return The color used to draw backbone bounds */ public Color getBackboneColor() { return _conf._backboneColor; } /** * Sets the color to be used for drawing backbone interactions. * * @param backbone_color * The new color for the backbone bounds */ public void setBackboneColor(Color backbone_color) { _conf._backboneColor = backbone_color; } /** * Returns the color used to display hydrogen bonds (base pairings) * * @return The color of hydrogen bonds */ public Color getBondColor() { return _conf._bondColor; } /** * Returns the title of this panel * * @return The title */ public String getTitle() { if (!_RNA.getName().equals("")) return _RNA.getName(); else return _conf._title; } /** * Sets the new color to be used for hydrogen bonds (base pairings) * * @param bond_color * The new color for hydrogen bonds */ public void setDefaultBPColor(Color bond_color) { _conf._bondColor = bond_color; } /** * Sets the size of the border, i.e. the empty space between the end of the * drawing area and the actual border. * * @param b * The new border size */ public void setBorderSize(Dimension b) { _border = b; } /** * Returns the size of the border, i.e. the empty space between the end of * the drawing area * * @return The border size */ public Dimension getBorderSize() { return _border; } /** * Sets the RNA to be displayed within this Panel. This method does not use * a drawing algorithm to reassigns base coordinates, rather assuming that * the RNA was previously drawn. * * @param r * An already drawn RNA to display in this panel */ public synchronized void showRNA(RNA r) { _RNA = r; } /** * Sets the RNA secondary structure to be drawn in this panel, using the * default layout algorithm. In addition to the raw nucleotides sequence, * the secondary structure is given in the so-called "Dot-bracket notation" * (DBN) format. This format is a well-parenthesized word over the alphabet * '(',')','.'.<br/> * Ex:<code>((((((((....))))..(((((...))).))))))</code><br /> * Returns <code>true</code> if the sequence/structure couple could be * parsed into a valid secondary structure, and <code>false</code> * otherwise. * * @param seq * The raw nucleotides sequence * @param str * The secondary structure * @throws ExceptionNonEqualLength */ public void drawRNA(String seq, String str) throws ExceptionNonEqualLength { drawRNA(seq, str, _RNA.get_drawMode()); } /** * Sets the RNA secondary structure to be drawn in this panel, using a given * layout algorithm. * * @param r * The new secondary structure * @param drawMode * The drawing algorithm */ public void drawRNA(RNA r, int drawMode) { r.setDrawMode(drawMode); drawRNA(r); } /** * Redraws the current RNA. This reassigns base coordinates to their default * value using the current drawing algorithm. */ public void drawRNA() { try { _RNA.drawRNA(_RNA.get_drawMode(),_conf); } catch (ExceptionNAViewAlgorithm e) { errorDialog(e); e.printStackTrace(); } repaint(); } /** * Sets the RNA secondary structure to be drawn in this panel, using the * current drawing algorithm. * * @param r * The new secondary structure */ public void drawRNA(RNA r) { if (r != null) { _RNA = r; drawRNA(); } } /** * Sets the RNA secondary structure to be drawn in this panel, using a given * layout algorithm. In addition to the raw nucleotides sequence, the * secondary structure is given in the so-called "Dot-bracket notation" * (DBN) format. This format is a well-parenthesized word over the alphabet * '(',')','.'.<br/> * Ex: <code>((((((((....))))..(((((...))).))))))</code><br /> * Returns <code>true</code> if the sequence/structure couple could be * parsed into a valid secondary structure, and <code>false</code> * otherwise. * * @param seq * The raw nucleotides sequence * @param str * The secondary structure * @param drawMode * The drawing algorithm * @throws ExceptionNonEqualLength */ public void drawRNA(String seq, String str, int drawMode) throws ExceptionNonEqualLength { _RNA.setDrawMode(drawMode); try { _RNA.setRNA(seq, str); drawRNA(); } catch (ExceptionUnmatchedClosingParentheses e) { errorDialog(e); } catch (ExceptionFileFormatOrSyntax e1) { errorDialog(e1); } } public void drawRNA(Reader r, int drawMode) throws ExceptionNonEqualLength, ExceptionFileFormatOrSyntax { _RNA.setDrawMode(drawMode); Collection<RNA> rnas = RNAFactory.loadSecStr(r); if (rnas.isEmpty()) { throw new ExceptionFileFormatOrSyntax("No RNA could be parsed from that source."); } _RNA = rnas.iterator().next(); drawRNA(); } /** * Draws a secondary structure of RNA using the default drawing algorithm * and displays it, using an interpolated transition between the previous * one and the new one. Extra bases, resulting from a size difference * between the two successive RNAs, are assumed to initiate from the middle * of the sequence. In other words, both prefixes and suffixes of the RNAs * are assumed to match, and what remains is an insertion. * * @param seq * Sequence * @param str * Structure in dot bracket notation * @throws ExceptionNonEqualLength * If len(seq)!=len(str) */ public void drawRNAInterpolated(String seq, String str) throws ExceptionNonEqualLength { drawRNAInterpolated(seq, str, _RNA.get_drawMode()); } /** * Draws a secondary structure of RNA using a given algorithm and displays * it, using an interpolated transition between the previous one and the new * one. Extra bases, resulting from a size difference between the two * successive RNAs, are assumed to initiate from the middle of the sequence. * In other words, both prefixes and suffixes of the RNAs are assumed to * match, and what remains is an insertion. * * @param seq * Sequence * @param str * Structure in dot bracket notation * @param drawMode * The drawing algorithm to be used for the initial placement * @throws ExceptionNonEqualLength * If len(seq)!=len(str) */ public void drawRNAInterpolated(String seq, String str, int drawMode) { drawRNAInterpolated(seq, str, drawMode, Mapping .DefaultOutermostMapping(_RNA.get_listeBases().size(), str .length())); } /** * Draws a secondary structure of RNA using the default drawing algorithm * and displays it, using an interpolated transition between the previous * one and the new one. Here, a mapping between those bases of the new * structure and the previous one is explicitly provided. * * @param seq * Sequence * @param str * Structure in dot bracket notation * @param m * A mapping between the currently rendered structure and its * successor (seq,str) * @throws ExceptionNonEqualLength * If len(seq)!=len(str) */ public void drawRNAInterpolated(String seq, String str, Mapping m) { drawRNAInterpolated(seq, str, _RNA.get_drawMode(), m); } /** * Draws a secondary structure of RNA using a given drawing algorithm and * displays it, using an interpolated transition between the previous one * and the new one. Here, a mapping between those bases of the new structure * and the previous one is provided. * * @param seq * Sequence * @param str * Structure in dot bracket notation * @param drawMode * The drawing algorithm to be used for the initial placement * @param m * A mapping between the currently rendered structure and its * successor (seq,str) */ public void drawRNAInterpolated(String seq, String str, int drawMode, Mapping m) { RNA target = new RNA(); try { target.setRNA(seq, str); drawRNAInterpolated(target, drawMode, m); } catch (ExceptionUnmatchedClosingParentheses e) { errorDialog(e); } catch (ExceptionFileFormatOrSyntax e) { errorDialog(e); } } /** * Draws a secondary structure of RNA using the default drawing algorithm * and displays it, using an interpolated transition between the previous * one and the new one. Here, a mapping between those bases of the new * structure and the previous one is explicitly provided. * * @param target * Secondary structure */ public void drawRNAInterpolated(RNA target) { drawRNAInterpolated(target, target.get_drawMode(), Mapping .DefaultOutermostMapping(_RNA.get_listeBases().size(), target .getSize())); } /** * Draws a secondary structure of RNA using the default drawing algorithm * and displays it, using an interpolated transition between the previous * one and the new one. Here, a mapping between those bases of the new * structure and the previous one is explicitly provided. * * @param target * Secondary structure * @param m * A mapping between the currently rendered structure and its * successor (seq,str) */ public void drawRNAInterpolated(RNA target, Mapping m) { drawRNAInterpolated(target, target.get_drawMode(), m); } /** * Draws a secondary structure of RNA using a given drawing algorithm and * displays it, using an interpolated transition between the previous one * and the new one. Here, a mapping between those bases of the new structure * and the previous one is provided. * * @param target * Secondary structure of RNA * @param drawMode * The drawing algorithm to be used for the initial placement * @param m * A mapping between the currently rendered structure and its * successor (seq,str) */ public void drawRNAInterpolated(RNA target, int drawMode, Mapping m) { try { target.drawRNA(drawMode,_conf); _conf._drawColorMap = false; _interpolator.addTarget(target, m); } catch (ExceptionNAViewAlgorithm e) { errorDialog(e); e.printStackTrace(); } } /** * Returns the current algorithm used for drawing the structure * * @return The current drawing algorithm */ public int getDrawMode() { return this._RNA.getDrawMode(); } public void showRNA(RNA t, VARNAConfig cfg) { showRNA(t); if (cfg!=null) { this.setConfig(cfg); } repaint(); } /** * Checks whether an interpolated transition bewteen two RNAs is occurring. * * @return True if an interpolated transition is occurring, false otherwise */ public boolean isInterpolationInProgress() { if (_interpolator == null) { return false; } else return _interpolator.isInterpolationInProgress(); } /** * Simply displays (does not redraw) a secondary structure , using an * interpolated transition between the previous one and the new one. A * default mapping between those bases of the new structure and the previous * one is used. * * @param target * Secondary structure of RNA */ public void showRNAInterpolated(RNA target) { showRNAInterpolated(target, Mapping.DefaultOutermostMapping(_RNA .get_listeBases().size(), target.getSize())); } /** * Simply displays (does not redraw) a secondary structure , using an * interpolated transition between the previous one and the new one. Here, a * mapping between bases of the new structure and the previous one is given. * * @param target * Secondary structure of RNA * @param m * A mapping between the currently rendered structure and its * successor (seq,str) * @throws ExceptionNonEqualLength * If len(seq)!=len(str) */ public void showRNAInterpolated(RNA target, Mapping m) { showRNAInterpolated(target, null,m); } public void showRNAInterpolated(RNA target, VARNAConfig cfg, Mapping m) { _interpolator.addTarget(target,cfg, m); } /** * When comparison mode is ON, sets the two RNA secondary structure to be * drawn in this panel, using a given layout algorithm. In addition to the * raw nucleotides sequence, the secondary structure is given in the * so-called "Dot-bracket notation" (DBN) format. This format is a * well-parenthesized word over the alphabet '(',')','.'.<br/> * Ex: <code>((((((((....))))..(((((...))).))))))</code><br /> * * @param firstSeq * The first RNA raw nucleotides sequence * @param firstStruct * The first RNA secondary structure * @param secondSeq * The second RNA raw nucleotides sequence * @param secondStruct * The second RNA secondary structure * @param drawMode * The drawing algorithm */ public void drawRNA(String firstSeq, String firstStruct, String secondSeq, String secondStruct, int drawMode) { _RNA.setDrawMode(drawMode); /** * Checking the sequences and structures validities... */ // This is a comparison, so the two RNA alignment past in parameters must // have the same sequence and structure length. if (firstSeq.length() == secondSeq.length() && firstStruct.length() == secondStruct.length()) { // First RNA if (firstSeq.length() != firstStruct.length()) { if (_conf._showWarnings) { emitWarning("First sequence length " + firstSeq.length() + " differs from that of it's secondary structure " + firstStruct.length() + ". \nAdapting first sequence length ..."); } if (firstSeq.length() < firstStruct.length()) { while (firstSeq.length() < firstStruct.length()) { firstSeq += " "; } } else { firstSeq = firstSeq.substring(0, firstStruct.length()); } } // Second RNA if (secondSeq.length() != secondStruct.length()) { if (_conf._showWarnings) { emitWarning("Second sequence length " + secondSeq.length() + " differs from that of it's secondary structure " + secondStruct.length() + ". \nAdapting second sequence length ..."); } if (secondSeq.length() < secondStruct.length()) { while (secondSeq.length() < secondStruct.length()) { secondSeq += " "; } } else { secondSeq = secondSeq.substring(0, secondStruct.length()); } } int RNALength = firstSeq.length(); String string_superStruct = new String(""); String string_superSeq = new String(""); /** * In this array, we'll have for each indexes of each characters of * the final super-structure, the RNA number which is own it. */ ArrayList<Integer> array_rnaOwn = new ArrayList<Integer>(); /** * Generating super-structure sequences and structures... */ firstStruct = firstStruct.replace('-', '.'); secondStruct = secondStruct.replace('-', '.'); // First of all, we make the structure for (int i = 0; i < RNALength; i++) { // If both characters are the same, so it'll be in the super // structure if (firstStruct.charAt(i) == secondStruct.charAt(i)) { string_superStruct = string_superStruct + firstStruct.charAt(i); array_rnaOwn.add(0); } // Else if one of the characters is an opening parenthese, so // it'll be an opening parenthese in the super structure else if (firstStruct.charAt(i) == '(' || secondStruct.charAt(i) == '(') { string_superStruct = string_superStruct + '('; array_rnaOwn.add((firstStruct.charAt(i) == '(') ? 1 : 2); } // Else if one of the characters is a closing parenthese, so // it'll be a closing parenthese in the super structure else if (firstStruct.charAt(i) == ')' || secondStruct.charAt(i) == ')') { string_superStruct = string_superStruct + ')'; array_rnaOwn.add((firstStruct.charAt(i) == ')') ? 1 : 2); } else { string_superStruct = string_superStruct + '.'; array_rnaOwn.add(-1); } } // Next, we make the sequence taking the characters at the same // index in the first and second sequence for (int i = 0; i < RNALength; i++) { string_superSeq = string_superSeq + firstSeq.charAt(i) + secondSeq.charAt(i); } // Now, we need to create the super-structure RNA with the owning // bases array // in order to color bases outer depending on the owning statement // of each bases. if (!string_superSeq.equals("") && !string_superStruct.equals("")) { try { _RNA.setRNA(string_superSeq, string_superStruct, array_rnaOwn); } catch (ExceptionUnmatchedClosingParentheses e) { errorDialog(e); } catch (ExceptionFileFormatOrSyntax e) { errorDialog(e); } } else { emitWarning("ERROR : The super-structure is NULL."); } switch (_RNA.get_drawMode()) { case RNA.DRAW_MODE_RADIATE: _RNA.drawRNARadiate(_conf); break; case RNA.DRAW_MODE_CIRCULAR: _RNA.drawRNACircle(); break; case RNA.DRAW_MODE_LINEAR: _RNA.drawRNALine(); break; case RNA.DRAW_MODE_NAVIEW: try { _RNA.drawRNANAView(); } catch (ExceptionNAViewAlgorithm e) { errorDialog(e); } break; default: break; } } } /** * Returns the currently selected base index, obtained through a mouse-left * click * * @return Selected base * public int getSelectedBaseIndex() { return _selectedBase; } /** * Returns the currently selected base, obtained through a mouse-left click * * @return Selected base * public ModeleBase getSelectedBase() { return _RNA.get_listeBases().get(_selectedBase); } /** * Sets the selected base index * * @param base * New selected base index * public void setSelectedBase(int base) { _selectedBase = base; }*/ /** * Returns the coordinates of the currently displayed RNA * * @return Coordinates array */ public Point2D.Double[] getRealCoords() { return _realCoords; } /** * Sets the coordinates of the currently displayed RNA * * @param coords * New coordinates */ public void setRealCoords(Point2D.Double[] coords) { _realCoords = coords; } /** * Returns the popup menu used for user mouse iteractions * * @return Popup menu */ public VueMenu getPopup() { return _popup; } /** * Sets the color used to display hydrogen bonds (base pairings) * * @param bond_color * The color of hydrogen bonds */ public void setBondColor(Color bond_color) { _conf._bondColor = bond_color; } /** * Returns the color used to draw the title * * @return The color used to draw the title */ public Color getTitleColor() { return _conf._titleColor; } /** * Sets the color used to draw the title * * @param title_color * The new color used to draw the title */ public void setTitleColor(Color title_color) { _conf._titleColor = title_color; } /** * Returns the height taken by the title * * @return The height taken by the title */ private int getTitleHeight() { return _titleHeight; } /** * Sets the height taken by the title * * @param title_height * The height taken by the title */ @SuppressWarnings("unused") private void setTitleHeight(int title_height) { _titleHeight = title_height; } /** * Returns the current state of auto centering mode. * * @return True if autocentered, false otherwise */ public boolean isAutoCentered() { return _conf._autoCenter; } /** * Sets the current state of auto centering mode. * * @param center * New auto-centered state */ public void setAutoCenter(boolean center) { _conf._autoCenter = center; } /** * Returns the font currently used for rendering the title. * * @return Current title font */ public Font getTitleFont() { return _conf._titleFont; } /** * Sets the font used for rendering the title. * * @param font * New title font */ public void setTitleFont(Font font) { _conf._titleFont = font; updateTitleHeight(); } /** * For the LINE_MODE drawing algorithm, sets the base pair height increment, * i.e. the vertical distance between two nested arcs. * * @return The current base pair increment */ public double getBPHeightIncrement() { return _RNA._bpHeightIncrement; } /** * Sets the base pair height increment, i.e. the vertical distance between * two arcs to be used in LINE_MODE. * * @param inc * New height increment */ public void setBPHeightIncrement(double inc) { _RNA._bpHeightIncrement = inc; } /** * Gets the scale factor used by the autofitting function * * @return Current scale factor */ public double getScaleFactor() { return _scaleFactor; } /** * Sets the scale factor used by the autofitting function * * @param factor * New scale factor */ public void setScaleFactor(double factor) { _scaleFactor = factor; } /** * Returns the shifting of the origin of the Panel in zoom mode * * @return The logical coordinate of the top-left panel point */ public Point2D.Double getOffsetPanel() { return _offsetPanel; } /** * Returns the vector bringing the logical coordinate of left-top-most point * in the panel to the left-top-most point of the RNA. * * @return The logical coordinate of the top-left panel point */ public Point2D.Double getRNAOffset() { return _offsetRNA; } /** * Returns this panel's UI menu * * @return Applet's UI popupmenu */ public VueMenu getPopupMenu() { return _popup; } /** * Returns the atomic zoom factor step, or increment. * * @return Atomic zoom factor increment */ public double getZoomIncrement() { return _conf._zoomAmount; } /** * Sets the atomic zoom factor step, or increment. * * @param amount * Atomic zoom factor increment */ public void setZoomIncrement(Object amount) { setZoomIncrement(Float.valueOf(amount.toString())); } /** * Sets the atomic zoom factor step, or increment. * * @param amount * Atomic zoom factor increment */ public void setZoomIncrement(double amount) { _conf._zoomAmount = amount; } /** * Returns the current zoom factor * * @return Current zoom factor */ public double getZoom() { return _conf._zoom; } /** * Sets the current zoom factor * * @param _zoom * New zoom factor */ public void setZoom(Object _zoom) { _conf._zoom = Float.valueOf(_zoom.toString()); } /** * Returns the translation used for zooming in and out * * @return A vector describing the translation */ public Point getTranslation() { return _translation; } /** * Sets the translation used for zooming in and out * * @param trans * A vector describing the new translation */ public void setTranslation(Point trans) { this._translation = trans; } /** * Returns the current RNA model * * @return Current RNA model */ public RNA getRNA() { return _RNA; } /** * Checks whether the drawn RNA is too large to be displayed, allowing for * shifting mouse interactions. * * @return true if the RNA is too large to be displayed, false otherwise */ public boolean isOutOfFrame() { return _horsCadre; } /** * Pops up an error Dialog displaying an exception in an human-readable way. * * @param error * The exception to display within the Dialog */ public void errorDialog(Exception error) { errorDialog(error, this); } /** * Pops up an error Dialog displaying an exception in an human-readable way * if errors are set to be displayed. * * @see #setErrorsOn(boolean) * @param error * The exception to display within the Dialog * @param c * Parent component for the dialog box */ public void errorDialog(Exception error, Component c) { if (isErrorsOn()) { JOptionPane.showMessageDialog(c, error.getMessage(), "VARNA Error", JOptionPane.ERROR_MESSAGE); } } /** * Pops up an error Dialog displaying an exception in an human-readable way. * * @param error * The exception to display within the Dialog * @param c * Parent component for the dialog box */ public static void errorDialogStatic(Exception error, Component c) { JOptionPane.showMessageDialog(c, error.getMessage(), "VARNA Critical Error", JOptionPane.ERROR_MESSAGE); } /** * Displays a warning message through a modal dialog if warnings are set to * be displayed. * * @see #setShowWarnings(boolean) * @param warning * A message expliciting the warning */ public void emitWarning(String warning) { if (_conf._showWarnings) JOptionPane.showMessageDialog(this, warning, "VARNA Warning", JOptionPane.WARNING_MESSAGE); } /** * Toggles modifications on and off * * @param modifiable * Modification status */ public void setModifiable(boolean modifiable) { _conf._modifiable = modifiable; } /** * Returns current modification status * * @return current modification status */ public boolean isModifiable() { return _conf._modifiable; } /** * Resets the visual aspects (Zoom factor, shift) for the Panel. */ public void reset() { this.setBorderSize(new Dimension(0, 0)); this.setTranslation(new Point(0, (int) (-getTitleHeight() / 2.0))); this.setZoom(VARNAConfig.DEFAULT_ZOOM); this.setZoomIncrement(VARNAConfig.DEFAULT_AMOUNT); } /** * Returns the color used to draw non-standard bases * * @return The color used to draw non-standard bases */ public Color getNonStandardBasesColor() { return _conf._specialBasesColor; } /** * Sets the color used to draw non-standard bases * * @param basesColor * The color used to draw non-standard bases */ public void setNonStandardBasesColor(Color basesColor) { _conf._specialBasesColor = basesColor; } /** * Checks if the current translation doesn't "kick" the whole RNA out of the * panel, and corrects the situation if necessary. */ public void checkTranslation() { // verification pour un zoom < 1 if (this.getZoom() <= 1) { // verification sortie gauche if (this.getTranslation().x < -(int) ((this.getWidth() - this .getInnerWidth()) / 2.0)) { this.setTranslation(new Point(-(int) ((this.getWidth() - this .getInnerWidth()) / 2.0), this.getTranslation().y)); } // verification sortie droite if (this.getTranslation().x > (int) ((this.getWidth() - this .getInnerWidth()) / 2.0)) { this.setTranslation(new Point((int) ((this.getWidth() - this .getInnerWidth()) / 2.0), this.getTranslation().y)); } // verification sortie bas if (this.getTranslation().y > (int) ((this.getHeight() - getTitleHeight() * 2 - this.getInnerHeight()) / 2.0)) { this.setTranslation(new Point(this.getTranslation().x, (int) ((this.getHeight() - getTitleHeight() * 2 - this .getInnerHeight()) / 2.0))); } // verification sortie haut if (this.getTranslation().y < -(int) ((this.getHeight() - this .getInnerHeight()) / 2.0)) { this .setTranslation(new Point(this.getTranslation().x, -(int) ((this.getHeight() - this .getInnerHeight()) / 2.0))); } } else { // zoom > 1 if (this.getTranslation().x < -(int) ((this.getInnerWidth()) / 2.0)) { this.setTranslation(new Point( -(int) ((this.getInnerWidth()) / 2.0), this .getTranslation().y)); } if (this.getTranslation().x > (int) ((this.getInnerWidth()) / 2.0)) { this.setTranslation(new Point( (int) ((this.getInnerWidth()) / 2.0), this .getTranslation().y)); } if (this.getTranslation().y < -(int) ((this.getInnerHeight()) / 2.0)) { this.setTranslation(new Point(this.getTranslation().x, -(int) ((this.getInnerHeight()) / 2.0))); } if (this.getTranslation().y > (int) ((this.getInnerHeight()) / 2.0)) { this.setTranslation(new Point(this.getTranslation().x, (int) ((this.getInnerHeight()) / 2.0))); } } } /** * Returns the "real pixels" x-coordinate of the RNA. * * @return X-coordinate of the translation */ public int getLeftOffset() { return _border.width + ((this.getWidth() - 2 * _border.width) - this.getInnerWidth()) / 2 + _translation.x; } /** * Returns the "real pixels" width of the drawing surface for our RNA. * * @return Width of the drawing surface for our RNA */ public int getInnerWidth() { // Largeur du dessin return (int) Math.round((this.getWidth() - 2 * _border.width) * _conf._zoom); } /** * Returns the "real pixels" y-coordinate of the RNA. * * @return Y-coordinate of the translation */ public int getTopOffset() { return _border.height + ((this.getHeight() - 2 * _border.height) - this .getInnerHeight()) / 2 + _translation.y; } /** * Returns the "real pixels" height of the drawing surface for our RNA. * * @return Height of the drawing surface for our RNA */ public int getInnerHeight() { // Hauteur du dessin return (int) Math.round((this.getHeight()) * _conf._zoom - 2 * _border.height - getTitleHeight()); } /** * Checks if the current mode is the "comparison" mode * * @return True if comparison, false otherwise */ public boolean isComparisonMode() { return _conf._comparisonMode; } /** * Rotates the RNA coordinates by a certain angle * * @param angleDegres * Rotation angle, in degrees */ public void globalRotation(Double angleDegres) { _RNA.globalRotation(angleDegres); fireLayoutChanged(); repaint(); } /** * Returns the index of the currently selected base, defaulting to the * closest base to the last mouse-click. * * @return Index of the currently selected base */ public Integer getNearestBase() { return _nearestBase; } /** * Sets the index of the currently selected base. * * @param base * Index of the new selected base */ public void setNearestBase(Integer base) { _nearestBase = base; } /** * Returns the color used to draw 'Gaps' bases in comparison mode * * @return Color used for 'Gaps' */ public Color getGapsBasesColor() { return _conf._dashBasesColor; } /** * Sets the color to use for 'Gaps' bases in comparison mode * * @param c * Color used for 'Gaps' */ public void setGapsBasesColor(Color c) { _conf._dashBasesColor = c; } @SuppressWarnings("unused") private void imprimer() { // PrintPanel canvas; // canvas = new PrintPanel(); PrintRequestAttributeSet attributes; attributes = new HashPrintRequestAttributeSet(); try { PrinterJob job = PrinterJob.getPrinterJob(); // job.setPrintable(this); if (job.printDialog(attributes)) { job.print(attributes); } } catch (PrinterException exception) { errorDialog(exception); } } /** * Checks whether errors are to be displayed * * @return Error display status */ public boolean isErrorsOn() { return _conf._errorsOn; } /** * Sets whether errors are to be displayed * * @param on * New error display status */ public void setErrorsOn(boolean on) { _conf._errorsOn = on; } /** * Returns the view associated with user interactions * * @return A view associated with user interactions */ public VueUI getVARNAUI() { return _UI; } /** * Toggles on/off using base inner color for drawing base-pairs * * @param on * True for using base inner color for drawing base-pairs, false * for classic mode */ public void setUseBaseColorsForBPs(boolean on) { _conf._useBaseColorsForBPs = on; } /** * Returns true if current base color is used as inner color for drawing * base-pairs * * @return True for using base inner color for drawing base-pairs, false for * classic mode */ public boolean getUseBaseColorsForBPs() { return _conf._useBaseColorsForBPs; } /** * Toggles on/off using a special color used for drawing "non-standard" * bases * * @param on * True for using a special color used for drawing "non-standard" * bases, false for classic mode */ public void setColorNonStandardBases(boolean on) { _conf._colorSpecialBases = on; } /** * Returns true if a special color is used as inner color for non-standard * base * * @return True for using a special color used for drawing "non-standard" * bases, false for classic mode */ public boolean getColorSpecialBases() { return _conf._colorSpecialBases; } /** * Toggles on/off using a special color used for drawing "Gaps" bases in * comparison mode * * @param on * True for using a special color used for drawing "Gaps" bases * in comparison mode, false for classic mode */ public void setColorGapsBases(boolean on) { _conf._colorDashBases = on; } /** * Returns true if a special color is used for drawing "Gaps" bases in * comparison mode * * @return True for using a special color used for drawing "Gaps" bases in * comparison mode, false for classic mode */ public boolean getColorGapsBases() { return _conf._colorDashBases; } /** * Toggles on/off displaying warnings * * @param on * True to display warnings, false otherwise */ public void setShowWarnings(boolean on) { _conf._showWarnings = on; } /** * Get current warning display status * * @return True to display warnings, false otherwise */ public boolean getShowWarnings() { return _conf._showWarnings; } /** * Toggles on/off displaying non-canonical base-pairs * * @param on * True to display NC base-pairs, false otherwise */ public void setShowNonCanonicalBP(boolean on) { _conf._drawnNonCanonicalBP = on; } /** * Return the current display status for non-canonical base-pairs * * @return True if NC base-pairs are displayed, false otherwise */ public boolean getShowNonCanonicalBP() { return _conf._drawnNonCanonicalBP; } /** * Toggles on/off displaying "non-planar" base-pairs * * @param on * True to display "non-planar" base-pairs, false otherwise */ public void setShowNonPlanarBP(boolean on) { _conf._drawnNonPlanarBP = on; } /** * Return the current display status for non-planar base-pairs * * @return True if non-planars base-pairs are displayed, false otherwise */ public boolean getShowNonPlanarBP() { return _conf._drawnNonPlanarBP; } /** * Sets the base-pair representation style * * @param st * The new base-pair style */ public void setBPStyle(VARNAConfig.BP_STYLE st) { _conf._mainBPStyle = st; } /** * Returns the base-pair representation style * * @return The current base-pair style */ public VARNAConfig.BP_STYLE getBPStyle() { return _conf._mainBPStyle; } /** * Returns the current VARNA Panel configuration. The returned instance * should not be modified directly, but rather through the getters/setters * from the VARNAPanel class. * * @return Current configuration */ public VARNAConfig getConfig() { return _conf; } /** * Sets the background color * * @param c * New background color */ public void setBackground(Color c) { if (_conf != null) { if (c!=null) { _conf._backgroundColor = c; _conf._drawBackground = (!c.equals(VARNAConfig.DEFAULT_BACKGROUND_COLOR)); } else { _conf._backgroundColor = VARNAConfig.DEFAULT_BACKGROUND_COLOR; _conf._drawBackground = false; } } } /** * Starts highlighting the selected base. */ public void highlightSelectedBase(ModeleBase m) { ArrayList<Integer> v = new ArrayList<Integer>(); int sel = m.getIndex(); if (sel != -1) { v.add(sel); } setSelection(v); } /** * Starts highlighting the selected base. */ public void highlightSelectedStem(ModeleBase m) { ArrayList<Integer> v = new ArrayList<Integer>(); int sel = m.getIndex(); if (sel != -1) { ArrayList<Integer> r = _RNA.findStem(sel); v.addAll(r); } setSelection(v); } public BaseList getSelection() { return _selectedBases; } public ArrayList<Integer> getSelectionIndices() { return _selectedBases.getIndices(); } public void setSelection(ArrayList<Integer> indices) { setSelection(_RNA.getBasesAt(indices)); } public void setSelection(Collection<? extends ModeleBase> mbs) { BaseList bck = new BaseList(_selectedBases); _selectedBases.clear(); _selectedBases.addBases(mbs); _blink.setActive(true); fireSelectionChanged(bck, _selectedBases); } public ArrayList<Integer> getBasesInRectangleDiff(Rectangle recIn, Rectangle recOut) { ArrayList<Integer> result = new ArrayList<Integer>(); for (int i=0;i<this._realCoords.length; i++) { if (recIn.contains(_realCoords[i]) ^ recOut.contains(_realCoords[i])) result.add(i); } return result; } public ArrayList<Integer> getBasesInRectangle(Rectangle rec) { ArrayList<Integer> result = new ArrayList<Integer>(); for (int i=0;i<this._realCoords.length; i++) { if (rec.contains(_realCoords[i])) result.add(i); } return result; } public void setSelectionRectangle(Rectangle rec) { ArrayList<Integer> result = new ArrayList<Integer>(); if (_selectionRectangle!=null) { result = getBasesInRectangleDiff(_selectionRectangle, rec); } else { result = getBasesInRectangle(rec); } _selectionRectangle = new Rectangle(rec); toggleSelection(result); repaint(); } public void removeSelectionRectangle() { _selectionRectangle = null; } public void addToSelection(Collection<? extends Integer> indices) { for(int i : indices) { addToSelection(i); } } public void addToSelection(int i) { BaseList bck = new BaseList(_selectedBases); ModeleBase mb = _RNA.getBaseAt(i); _selectedBases.addBase(mb); _blink.setActive(true); fireSelectionChanged(bck, _selectedBases); } public void removeFromSelection(int i) { BaseList bck = new BaseList(_selectedBases); ModeleBase mb = _RNA.getBaseAt(i); _selectedBases.removeBase(mb); if (_selectedBases.size()==0) { _blink.setActive(false); } else { _blink.setActive(true); } fireSelectionChanged(bck, _selectedBases); } public boolean isInSelection(int i) { return _selectedBases.contains(_RNA.getBaseAt(i)); } public void toggleSelection(int i) { if (isInSelection(i)) removeFromSelection(i); else addToSelection(i); } public void toggleSelection(Collection<? extends Integer> indices) { for(int i : indices) { toggleSelection(i); } } /** * Stops highlighting bases */ public void clearSelection() { BaseList bck = new BaseList(_selectedBases); _selectedBases.clear(); _blink.setActive(false); repaint(); fireSelectionChanged(bck, _selectedBases); } public void saveSelection() { _backupSelection.clear(); _backupSelection.addAll(_selectedBases.getBases()); } public void restoreSelection() { setSelection(_backupSelection); } /** * Stops highlighting bases */ public void resetAnnotationHighlight() { _highlightAnnotation = false; repaint(); } /** * Toggles on/off a rectangular outline of the bounding box. * * @param on * True to draw the bounding box, false otherwise */ public void drawBBox(boolean on) { _drawBBox = on; } /** * Toggles on/off a rectangular outline of the border. * * @param on * True to draw the bounding box, false otherwise */ public void drawBorder(boolean on) { _drawBorder = on; } public void setBaseInnerColor(Color c) { _RNA.setBaseInnerColor(c); } public void setBaseNumbersColor(Color c) { _RNA.setBaseNumbersColor(c); } public void setBaseNameColor(Color c) { _RNA.setBaseNameColor(c); } public void setBaseOutlineColor(Color c) { _RNA.setBaseOutlineColor(c); } public ArrayList<TextAnnotation> getListeAnnotations() { return _RNA.getAnnotations(); } public void resetListeAnnotations() { _RNA.clearAnnotations(); repaint(); } public void addAnnotation(TextAnnotation textAnnotation) { _RNA.addAnnotation(textAnnotation); repaint(); } public boolean removeAnnotation(TextAnnotation textAnnotation) { boolean done = _RNA.removeAnnotation(textAnnotation); repaint(); return done; } public TextAnnotation get_selectedAnnotation() { return _selectedAnnotation; } public void set_selectedAnnotation(TextAnnotation annotation) { _selectedAnnotation = annotation; } public void removeSelectedAnnotation() { _highlightAnnotation = false; _selectedAnnotation = null; } public void highlightSelectedAnnotation() { _highlightAnnotation = true; } public boolean getFlatExteriorLoop() { return _conf._flatExteriorLoop; } public void setFlatExteriorLoop(boolean on) { _conf._flatExteriorLoop = on; } public void setLastSelectedPosition(Point2D.Double p) { _lastSelectedCoord.x = p.x; _lastSelectedCoord.y = p.y; } public Point2D.Double getLastSelectedPosition() { return _lastSelectedCoord; } public void setSequence(String s) { _RNA.setSequence(s); repaint(); } public void setColorMapVisible(boolean b) { _conf._drawColorMap = b; repaint(); } public boolean getColorMapVisible() { return _conf._drawColorMap; } public void removeColorMap() { _conf._drawColorMap = false; repaint(); } public void saveSession(String path) { FileOutputStream fos = null; ObjectOutputStream out = null; try { fos = new FileOutputStream(path); out = new ObjectOutputStream(fos); out.writeObject(new FullBackup(_conf,_RNA,_conf._title)); out.close(); } catch(Exception ex) { ex.printStackTrace(); } } public FullBackup loadSession(String path) throws ExceptionLoadingFailed { FullBackup bck = importSession(path); Mapping map = Mapping.DefaultOutermostMapping(getRNA().getSize(), bck.rna.getSize()); showRNAInterpolated(bck.rna,map); _conf = bck.config; repaint(); return bck; } public static String VARNA_SESSION_EXTENSION = "varna"; public static FullBackup importSession(String path) throws ExceptionLoadingFailed { try { return importSession(new FileInputStream(path),path); } catch (FileNotFoundException e) { throw (new ExceptionLoadingFailed("File not found.",path)); } } public static FullBackup importSession(InputStream fis, String path) throws ExceptionLoadingFailed { FullBackup bck = null; ObjectInputStream in = null; try { in = new ObjectInputStream(fis); bck = (FullBackup) in.readObject(); in.close(); return bck; } catch(IOException ex) { throw new ExceptionLoadingFailed("I/O error while reading VARNA session", path); } catch(ClassNotFoundException ex) { throw new ExceptionLoadingFailed("Bad format while reading VARNA session", path); } } public void loadFile(String path) { loadFile(path,false); } public boolean getDrawBackbone() { return _conf._drawBackbone; } public void setDrawBackbone(boolean b) { _conf._drawBackbone = b; } public void addHighlightRegion(HighlightRegionAnnotation n) { _RNA.addHighlightRegion(n); } public void removeHighlightRegion(HighlightRegionAnnotation n) { _RNA.removeHighlightRegion(n); } public void addHighlightRegion(int i, int j) { _RNA.addHighlightRegion(i, j); } public void addHighlightRegion(int i, int j, Color fill, Color outline, double radius) { _RNA.addHighlightRegion(i, j,fill, outline,radius); } public void loadFile(String path, boolean interpolate) { try{ loadSession(path); } catch(Exception e1) { try { Collection<RNA> rnas = RNAFactory.loadSecStr(path); if (rnas.isEmpty()) { throw new ExceptionFileFormatOrSyntax("No RNA could be parsed from that source."); } RNA rna = rnas.iterator().next(); try { rna.drawRNA(_conf); } catch (ExceptionNAViewAlgorithm e) { e.printStackTrace(); } if (!interpolate) { showRNA(rna); } else { this.showRNAInterpolated(rna); } } catch (FileNotFoundException e) { e.printStackTrace(); } catch (ExceptionFileFormatOrSyntax e) { e.printStackTrace(); }catch (Exception e) { e.printStackTrace(); } } } public void setConfig(VARNAConfig cfg) { _conf = cfg; } public void toggleDrawOutlineBase() { _conf._drawOutlineBase = !_conf._drawOutlineBase; } public void toggleFillBase() { _conf._fillBase =!_conf._fillBase; } public void readValues(Reader r) { this._RNA.readValues(r, _conf._cm); } public void addVARNAListener(InterfaceVARNAListener v) { _VARNAListeners.add(v); } public void fireLayoutChanged() { for(InterfaceVARNAListener v: _VARNAListeners) { v.onStructureRedrawn(); } } public void fireUINewStructure() { for(InterfaceVARNAListener v: _VARNAListeners) { v.onUINewStructure(_conf,_RNA ); } } public void addSelectionListener(InterfaceVARNASelectionListener v) { _selectionListeners.add(v); } public void fireSelectionChanged(BaseList mold, BaseList mnew) { BaseList addedBases = mnew.removeAll(mold); BaseList removedBases = mold.removeAll(mnew); for(InterfaceVARNASelectionListener v2: _selectionListeners) { v2.onSelectionChanged(mnew, addedBases, removedBases); } } public void fireHoverChanged(ModeleBase mold, ModeleBase mnew) { for(InterfaceVARNASelectionListener v2: _selectionListeners) { v2.onHoverChanged(mold, mnew); } } public void addRNAListener(InterfaceVARNARNAListener v) { _RNAListeners.add(v); } public void fireSequenceChanged(int index, String oldseq, String newseq) { for(InterfaceVARNARNAListener v2: _RNAListeners) { v2.onSequenceChanged(index,oldseq,newseq); } } public void fireStructureChanged(Set<ModeleBP> current, Set<ModeleBP> addedBasePairs, Set<ModeleBP> removedBasePairs) { for(InterfaceVARNARNAListener v2: _RNAListeners) { v2.onStructureChanged(current, addedBasePairs, removedBasePairs); } } public void fireLayoutChanged(Hashtable<Integer,Point2D.Double> movedPositions) { for(InterfaceVARNARNAListener v2: _RNAListeners) { v2.onLayoutChanged(movedPositions); } } public double getOrientation() { return _RNA.getOrientation(); } public ModeleBase _hoveredBase = null; public void setHoverBase(ModeleBase m) { if (m!=_hoveredBase) { ModeleBase bck = _hoveredBase; _hoveredBase = m; repaint(); fireHoverChanged(bck, m); } } }