/*
* This file is part of ADDIS (Aggregate Data Drug Information System).
* ADDIS is distributed from http://drugis.org/.
* Copyright © 2009 Gert van Valkenhoef, Tommi Tervonen.
* Copyright © 2010 Gert van Valkenhoef, Tommi Tervonen, Tijs Zwinkels,
* Maarten Jacobs, Hanno Koeslag, Florin Schimbinschi, Ahmad Kamal, Daniel
* Reid.
* Copyright © 2011 Gert van Valkenhoef, Ahmad Kamal, Daniel Reid, Florin
* Schimbinschi.
* Copyright © 2012 Gert van Valkenhoef, Daniel Reid, Joël Kuiper, Wouter
* Reckman.
* Copyright © 2013 Gert van Valkenhoef, Joël Kuiper.
*
* This program is free software: you can redistribute it and/or modify
* it under the terms of the GNU General Public License as published by
* the Free Software Foundation, either version 3 of the License, or
* (at your option) any later version.
*
* This program is distributed in the hope that it will be useful,
* but WITHOUT ANY WARRANTY; without even the implied warranty of
* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
* GNU General Public License for more details.
*
* You should have received a copy of the GNU General Public License
* along with this program. If not, see <http://www.gnu.org/licenses/>.
*/
package org.drugis.addis.entities.relativeeffect;
import org.drugis.addis.entities.Measurement;
import org.drugis.mtc.summary.QuantileSummary;
public class NetworkRelativeEffect<T extends Measurement> extends AbstractRelativeEffect<T> implements RelativeEffect<T> {
private QuantileSummary d_quantiles;
private final boolean d_defined;
private boolean d_isLogTransformed = false;
public NetworkRelativeEffect(QuantileSummary q, boolean isLogTransformed) {
d_isLogTransformed = isLogTransformed;
d_quantiles = q;
d_defined = true;
}
public NetworkRelativeEffect() {
d_defined = false;
}
static public NetworkRelativeEffect<? extends Measurement> buildOddsRatio(QuantileSummary estimate) {
return new NetworkRelativeEffect<Measurement>(estimate, true);
}
static public NetworkRelativeEffect<? extends Measurement> buildMeanDifference(QuantileSummary estimate) {
return new NetworkRelativeEffect<Measurement>(estimate, false);
}
public String getName() {
return "Network Meta-Analysis Relative Effect";
}
public boolean isDefined() {
return d_defined;
}
@Override
public ConfidenceInterval getConfidenceInterval() {
if (!isDefined()) {
return new ConfidenceInterval(Double.NaN, Double.NaN, Double.NaN);
}
if(d_isLogTransformed) {
return new ConfidenceInterval(Math.exp(d_quantiles.getQuantile(d_quantiles.indexOf(0.5))), Math.exp(d_quantiles.getQuantile(d_quantiles.indexOf(0.025))), Math.exp(d_quantiles.getQuantile(d_quantiles.indexOf((0.975)))));
} else {
return new ConfidenceInterval(d_quantiles.getQuantile(d_quantiles.indexOf(0.5)), d_quantiles.getQuantile(d_quantiles.indexOf(0.025)), d_quantiles.getQuantile(d_quantiles.indexOf(0.975)));
}
}
@Override
@Deprecated
public Distribution getDistribution() {
double mean = d_quantiles.getQuantile(d_quantiles.indexOf(0.5));
double stdev = (d_quantiles.getQuantile(d_quantiles.indexOf(0.975)) - d_quantiles.getQuantile(d_quantiles.indexOf(0.025))) / (2 * 1.960);
if(d_isLogTransformed) {
return new Gaussian(mean, stdev);
} else {
return new LogGaussian(mean, stdev);
}
}
@Override
public AxisType getAxisType() {
return d_isLogTransformed ? AxisType.LOGARITHMIC : AxisType.LINEAR;
}
}