/* * Copyright (C) 2013 Vinu K.N * * This program is free software: you can redistribute it and/or modify * it under the terms of the GNU General Public License as published by * the Free Software Foundation, either version 3 of the License, or * (at your option) any later version. * * This program is distributed in the hope that it will be useful, * but WITHOUT ANY WARRANTY; without even the implied warranty of * MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the * GNU General Public License for more details. * * You should have received a copy of the GNU General Public License * along with this program. If not, see <http://www.gnu.org/licenses/>. */ package org.domainmath.gui.bioinfo.multi_seq_viewer; import java.awt.AlphaComposite; import java.awt.BorderLayout; import java.awt.Color; import java.awt.Component; import java.awt.EventQueue; import java.awt.Font; import java.awt.Graphics; import java.awt.Graphics2D; import java.awt.Insets; import java.awt.Point; import java.awt.Rectangle; import java.awt.Shape; import java.awt.SystemColor; import java.awt.event.MouseEvent; import java.awt.event.MouseListener; import java.awt.event.MouseMotionListener; import java.awt.geom.Path2D; import java.io.File; import java.io.FileInputStream; import java.util.ArrayList; import java.util.Collections; import java.util.LinkedHashMap; import java.util.List; import java.util.Map; import javax.swing.BorderFactory; import javax.swing.DefaultListModel; import javax.swing.JLabel; import javax.swing.JList; import javax.swing.JPanel; import javax.swing.JScrollPane; import javax.swing.JSplitPane; import javax.swing.ListCellRenderer; import javax.swing.ListModel; import javax.swing.ListSelectionModel; import javax.swing.border.Border; import javax.swing.border.EmptyBorder; import javax.swing.plaf.basic.BasicGraphicsUtils; import org.biojava3.alignment.Alignments; import org.biojava3.alignment.template.AlignedSequence; import org.biojava3.alignment.template.Profile; import org.biojava3.core.sequence.ProteinSequence; import org.biojava3.core.sequence.compound.AminoAcidCompound; import org.biojava3.core.sequence.compound.AminoAcidCompoundSet; import org.biojava3.core.sequence.io.FastaReader; import org.biojava3.core.sequence.io.GenericFastaHeaderParser; import org.biojava3.core.sequence.io.ProteinSequenceCreator; public class MultiSeqViewerPanel extends javax.swing.JPanel { private List data =Collections.synchronizedList(new ArrayList()); private List col =Collections.synchronizedList(new ArrayList()); public List header =Collections.synchronizedList(new ArrayList()); public List Sequence =Collections.synchronizedList(new ArrayList()); private DefaultListModel listConsensusModel; public JList listConsensus; private JSplitPane splitPane; private DefaultListModel listSequenceModel; public JList listSequence; public Path2D polygon = null; private final Font fontListConsensus; private int listRowCount; private List<AlignedSequence<ProteinSequence, AminoAcidCompound>> p; public MultiSeqViewerPanel(File f){ fontListConsensus = new Font("Monospaced",Font.BOLD,11); listConsensusModel = new DefaultListModel(); listConsensus = new JList(); listConsensus.setFont(fontListConsensus); listConsensus.setModel(listConsensusModel); listConsensus.setSelectedIndex(0); listConsensus.setSelectionMode(ListSelectionModel.SINGLE_SELECTION); listSequenceModel = new DefaultListModel(); listSequence = new JList() { private SeqListCellRenderer renderer; private AlphaComposite alcomp = AlphaComposite.getInstance(AlphaComposite.SRC_OVER, 0.1f); private Color PCOLOR; @Override public void updateUI() { setSelectionForeground(null); setSelectionBackground(null); setCellRenderer(null); if(renderer!=null) { removeMouseMotionListener(renderer); removeMouseListener(renderer); }else{ renderer = new SeqListCellRenderer(); } super.updateUI(); EventQueue.invokeLater(new Runnable() { @Override public void run() { setCellRenderer(renderer); addMouseMotionListener(renderer); addMouseListener(renderer); } }); Color c = getSelectionBackground(); int r = c.getRed(), g = c.getGreen(), b = c.getBlue(); PCOLOR = r>g ? r>b ? new Color(r,0,0) : new Color(0,0,b) : g>b ? new Color(0,g,0) : new Color(0,0,b); } @Override public void paintComponent(Graphics g) { super.paintComponent(g); if(renderer.polygon!=null) { Graphics2D g2d = (Graphics2D) g; g2d.setPaint(getSelectionBackground()); g2d.draw(renderer.polygon); g2d.setComposite(alcomp); g2d.setPaint(PCOLOR); g2d.fill(renderer.polygon); } } }; listSequence.setLayoutOrientation(JList.HORIZONTAL_WRAP); listSequence.setSelectionMode(ListSelectionModel.MULTIPLE_INTERVAL_SELECTION); listSequence.setModel(listSequenceModel); getFasta(f); splitPane= new JSplitPane(JSplitPane.HORIZONTAL_SPLIT,new JScrollPane(listConsensus),new JScrollPane(listSequence)); splitPane.setDividerLocation(250); listConsensus.addMouseListener(new MouseListener() { @Override public void mouseClicked(MouseEvent e) { int r = getRowCount()/listConsensusModel.getSize(); int c =r*listConsensus.getSelectedIndex(); int c_end =c+(r); ListSelectionModel sm = listSequence.getSelectionModel(); sm.clearSelection(); int size = listSequence.getModel().getSize(); for (int i=c; i<c_end;i++ ) { if (i < size) { sm.addSelectionInterval(i, i); } } } @Override public void mousePressed(MouseEvent e) { } @Override public void mouseReleased(MouseEvent e) { } @Override public void mouseEntered(MouseEvent e) { } @Override public void mouseExited(MouseEvent e) { } }); setLayout(new BorderLayout()); add(splitPane,BorderLayout.CENTER); repaint(); } public void addRow(String r) { data.add(r); } public void addCol(String c) { col.add(c); } private void getFasta(File selectedFile) { try{ String[] t ; String s; FileInputStream inStream = new FileInputStream( selectedFile ); FastaReader<ProteinSequence,AminoAcidCompound> fastaReader = new FastaReader<>( inStream, new GenericFastaHeaderParser<ProteinSequence,AminoAcidCompound>(), new ProteinSequenceCreator(AminoAcidCompoundSet.getAminoAcidCompoundSet())); LinkedHashMap<String, ProteinSequence> b = fastaReader.process(); for ( Map.Entry<String, ProteinSequence> entry : b.entrySet() ) { listConsensusModel.addElement(entry.getValue().getOriginalHeader()); this.header.add(entry.getValue().getOriginalHeader()); this.Sequence.add(entry.getValue()); } Profile<ProteinSequence, AminoAcidCompound> profile = Alignments.getMultipleSequenceAlignment(Sequence); p =profile.getAlignedSequences(); for(int i=0; i<p.size(); i++) { s=p.get(i).getSequenceAsString(); t =s.split(""); for(int j=0; j<t.length; j++) { listSequenceModel.addElement(t[j]); } } int k=0; for(int i=0; i<listSequenceModel.getSize(); i++) { if(listSequenceModel.get(i)==null || listSequenceModel.get(i).equals("\n") || listSequenceModel.get(i).equals("") ) { k++; listSequenceModel.remove(i); } } listSequence.setVisibleRowCount(k); this.setRowCount(listSequenceModel.getSize()); }catch(Exception e) { } } public int getCountListlistConsensus() { return this.listConsensus.getModel().getSize(); } /** * This method is called from within the constructor to initialize the form. * WARNING: Do NOT modify this code. The content of this method is always * regenerated by the Form Editor. */ @SuppressWarnings("unchecked") // <editor-fold defaultstate="collapsed" desc="Generated Code">//GEN-BEGIN:initComponents private void initComponents() { javax.swing.GroupLayout layout = new javax.swing.GroupLayout(this); this.setLayout(layout); layout.setHorizontalGroup( layout.createParallelGroup(javax.swing.GroupLayout.Alignment.LEADING) .addGap(0, 400, Short.MAX_VALUE) ); layout.setVerticalGroup( layout.createParallelGroup(javax.swing.GroupLayout.Alignment.LEADING) .addGap(0, 300, Short.MAX_VALUE) ); }// </editor-fold>//GEN-END:initComponents private void setRowCount(int k) { this.listRowCount = k; } public int getRowCount() { return this.listRowCount; } // Variables declaration - do not modify//GEN-BEGIN:variables // End of variables declaration//GEN-END:variables class DotBorder extends EmptyBorder { public DotBorder(Insets borderInsets) { super(borderInsets); } public DotBorder(int top, int left, int bottom, int right) { super(top, left, bottom, right); } @Override public boolean isBorderOpaque() {return true;} @Override public void paintBorder(Component c, Graphics g, int x, int y, int w, int h) { Graphics2D g2 = (Graphics2D)g; g2.translate(x,y); g2.setPaint(new Color(~SystemColor.activeCaption.getRGB())); BasicGraphicsUtils.drawDashedRect(g2, 0, 0, w, h); g2.translate(-x,-y); } } class SeqListCellRenderer extends JPanel implements ListCellRenderer, MouseListener, MouseMotionListener { private final JLabel label = new JLabel("", JLabel.CENTER); private final Border dotBorder = new DotBorder(2,2,2,2); private final Border empBorder = BorderFactory.createEmptyBorder(2,2,2,2); private final Point srcPoint = new Point(); public Path2D polygon = null; public SeqListCellRenderer() { super(new BorderLayout()); label.setOpaque(true); label.setForeground(getForeground()); label.setBackground(getBackground()); this.setOpaque(false); this.add(label, BorderLayout.CENTER); } @Override public Component getListCellRendererComponent(JList list, Object value, int index, boolean isSelected, boolean cellHasFocus) { String item = value.toString(); label.setText(item); label.setBorder(cellHasFocus?dotBorder:empBorder); setRasmolColorSheme(label,item,isSelected); return this; } @Override public void mouseMoved(MouseEvent e) {} @Override public void mouseDragged(MouseEvent e) { JList list = (JList)e.getSource(); list.setFocusable(true); if(polygon==null){ srcPoint.setLocation(e.getPoint()); } Point destPoint = e.getPoint(); polygon = new Path2D.Double(); polygon.moveTo(srcPoint.x, srcPoint.y); polygon.lineTo(destPoint.x, srcPoint.y); polygon.lineTo(destPoint.x, destPoint.y); polygon.lineTo(srcPoint.x, destPoint.y); polygon.closePath(); list.setSelectedIndices(getIntersectsIcons(list, polygon)); list.repaint(); } @Override public void mouseClicked(MouseEvent e) {} @Override public void mouseEntered(MouseEvent e) {} @Override public void mouseExited(MouseEvent e) {} @Override public void mouseReleased(MouseEvent e) { JList list = (JList)e.getSource(); list.setFocusable(true); polygon = null; list.repaint(); } @Override public void mousePressed(MouseEvent e) { JList list = (JList)e.getSource(); int index = list.locationToIndex(e.getPoint()); Rectangle rect = list.getCellBounds(index,index); if(!rect.contains(e.getPoint())) { list.clearSelection(); list.getSelectionModel().setAnchorSelectionIndex(-1); list.getSelectionModel().setLeadSelectionIndex(-1); //list.getSelectionModel().setLeadSelectionIndex(list.getModel().getSize()); list.setFocusable(false); }else{ list.setFocusable(true); } } private int[] getIntersectsIcons(JList l, Shape p) { ListModel model = l.getModel(); ArrayList<Integer> list = new ArrayList<>(model.getSize()); for(int i=0;i<model.getSize();i++) { Rectangle r = l.getCellBounds(i,i); if(p.intersects(r)) { list.add(i); } } int[] il = new int[list.size()]; for(int i=0;i<list.size();i++) { il[i] = list.get(i); } return il; } private void setRasmolColorSheme(JLabel label,String item,boolean isSelected) { if(isSelected) { label.setForeground(listConsensus.getSelectionForeground()); label.setBackground(listConsensus.getSelectionBackground()); }else{ if(item.equalsIgnoreCase("A")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(200,200,200)); }else if(item.equalsIgnoreCase("C") || item.equalsIgnoreCase("M")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(230,230,0)); }else if(item.equalsIgnoreCase("N") || item.equalsIgnoreCase("Q")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color( 0,220,220)); }else if(item.equalsIgnoreCase("I") || item.equalsIgnoreCase("L") || item.equalsIgnoreCase("V")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(15,130,15)); }else if(item.equalsIgnoreCase("F")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(20,90,255)); }else if(item.equalsIgnoreCase("H")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(130,130,210)); }else if(item.equalsIgnoreCase("K") || item.equalsIgnoreCase("R")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(20,90,255)); }else if(item.equalsIgnoreCase("G")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(235,235,235)); }else if(item.equalsIgnoreCase("S") || item.equalsIgnoreCase("T")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(250,150,0)); }else if(item.equalsIgnoreCase("D") || item.equalsIgnoreCase("E")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(230,10,10)); }else if(item.equalsIgnoreCase("Y")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(50,50,170)); }else if(item.equalsIgnoreCase("B") || item.equalsIgnoreCase("Z") || item.equalsIgnoreCase("X")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(190,160,110)); }else if(item.equalsIgnoreCase("P")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(220,150,130)); }else if(item.equalsIgnoreCase("W")) { label.setForeground(listConsensus.getForeground()); label.setBackground(new Color(180,90,180)); } else{ label.setForeground(listConsensus.getForeground()); label.setBackground(listConsensus.getBackground()); } } } } }